Updated on April 4, 2017
Cheers to a new week everybody.
I expect to have a couple really cool exclusive posts to present later in the week, and for now I wanted to check in and say hello. I’m going to be adding a mixture of posts that will be weekly round-ups and insights that I believe to be valuable.
This post is titled “Gratitude.” After sharing some news last week it became clear to me that gratitude is such an important part of a hair-restoration seeker’s life. I would love to see much more gratitude in online hair discussion. Most of us are eagerly anticipating the next effective treatment to become approved and available. In the meantime, the online hair-growth-treatment world looks something like this: News of potential treatments that have shown great results on mice abound, we occasionally hear important news from companies that are already in human trials. Is any of this worth getting happy about and getting our hopes up? I would say of course it is. Every piece of work counts. When the ultimate stem-cell hair regeneration treatment that restores full heads of hair becomes available, it is almost certain it would have started out being tested on mice. So why not enjoy it when you hear about a new approach and a new study that has shown good results? Read More
Updated on May 1, 2017
One topic that I feel could use more attention in the hair regeneration world is scar repair for people who have underwent FUT hair transplants. I felt that it was a good time to bring up this subject alongside the publication from Dr. Luis Garza on TLR3 that came out this week. I will provide more feedback on the TLR3 discovery in a separate article. Currently, people deal with FUT scar repair by implanting hairs into the scars. Scalp donor hair and sometimes body hair is used to fill in FUT transplant scars. Read More
Updated on May 1, 2017
Follicle Thought is proud to present this exclusive preclinical research data courtesy of Dr. Jan Alenfall of Follicum. Jan has provided me with a personal write-up on Follicum’s lead candidate drug, FOL-S-005, as well as two research data graphs. I have added the write-up to the original Follicum post.
Below are two graphs demonstrating the efficacy of Follicum’s compounds. Both graphs display results that were obtained from mice. The first graph depicts the results of 6 of Follicum’s potential compounds. The second graph shows the results of minoxidil over a 30 day period. Here’s a quote from Dr. Alenfall about these graphs: “All these results were generated by the contract research laboratory that compared the effectiveness of our compounds compared with minoxidil (the active ingredient in Rogaine®), however the minoxidil study was carried out separately by the laboratory using exactly the same experimental conditions.” Jan also told me that Follicum only intends to move forward with the compounds that show the most promise. I’d say there’s a few here. One thing that’s important to pay attention to is the number of days that it took for these compounds to achieve their results.
Originally, I coupled this write-up in the previous Skin and Hair Regeneration for Transplant Donor Area post, but I decided to expand upon it and give it its own post.
The main idea of the latest research article by Luis Garza et al is a protein called toll-like recepter 3 (TLR3) was found to be a major proponent of skin and hair regeneration during wound healing. TLR3 does this by sensing and reacting to the double-stranded RNA (dsRNA) which is released by damaged skin. This quote from Dr. Garza probably says it all “Medications that turn on this protein have the powerful potential to decrease scarring as healing of wounds takes place, thereby promoting skin and hair follicle regeneration.” He also mentions that drug companies are already developing TLR3 activators for uses on the immune system and those products could be tested for hair regeneration purposes also. That would be similar to the Cotsarelis PGD2-Setipriprant deal. Read More
BiologicsMD, a biotechnology start-up out of Fayetville, Arkansas, has recently been granted a patent for a protein named “BMD-2341” that has been said to promote hair growth or prevent hair loss. The patent is titled ““Fusion Proteins of Collagen Binding-Domain and Parathyroid Hormone.” This news comes in the latest press release from BiologicsMD. Read More
In memory of Devon Grimme who has passed away since the publishing of this interview.
Follicle Thought is proud to present this exclusive interview with the two major figures of Follicept, Devon Grimme and Dr. Stephen Hsu. There’s a few goodies in here that I have not seen mentioned on the Follicept message board. Many thanks to Devon and Dr. Hsu, and without further ado here is the interview: Read More
Sanford-Burnham Medical Research Institute just received a generous donation to the tune of $100 million. The donation has prompted them to change their name to Sanford Burnham Prebys Medical Discovery Institute, incorporating the name of Conrad Prebys, their latest benefactor. Read More
I just wanted to let you know that I’ve added a new email subscription sign-up on the right sidebar of the page. You simply enter your email and you will receive a notification every time I post a new article to the site.
Also, I’ve added a Twitter follow button on the side bar as well. 🙂 I’m new to the web development stuff. Just taking it one step at a time. The important thing is I am able to provide you all the best news on hair regeneration and insight on each situation.
Thanks for your continued support,
Updated on May 1, 2017
The school has one of the most advanced regenerative medicine programs in the country. According to the Wake Forest website, they are currently gearing up for a clinical trial on a “topical investigational medication” for hair. At the bottom of the page there is still a link button to sign up and participate in the study, but according to members of the hair forums, the trial is already filled up. That’s not awful news. WF should be all set to go ahead and start this trial then. (Update: since this article was written the webpage was taken down) In other recent news… Read More
Updated on May 2, 2017
The research led by Alexey Terskikh at Sanford-Burnham Medical Research Institute has grown very popular on the internet over the past several months. The work was even featured in our Ultimate Guide to Hair Regeneration a few months ago. Terskikh’s technology is based on taking human pluripotent stem cells, programming them to differentiate into dermal papillae cells, and then injecting those DP cells back into a scalp to grow hair. Terskikh notes that his method is superior to another popular method of extracting DP cells directly from a scalp and culturing them to be re-injected, because there are issues about DP cells’ ability to induce hair follicle formation after being outside the body. Read More