Updates – Cures For Hair Loss 2018

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More Fun More Follicum (2/7/18)

Follicum’s new phase 2a study for the scalp has been approved by the German Medicines Agency. The study is expected to be completed in 2018 and more importantly, results from the study are expected to be announced in 2018 as well. Press release here.

New Follicum Interview (2/6/18)

New Youtube video  interview with Follicum CEO Jan Alenfall here

Yokohama University Hair Follicle Cloning (2/5/18)

I must have had about 5 readers email me today about the fascinating research coming out of Yokohama National University in Japan. Professor Junji Fukuda lead the efforts to successfully prepare “hair follicle germs” at large scale simultaneously. Essentially, the researchers prepared a cellular formulation with the right culturing materials to promote successful growth and development of tiny “hair follicle starter kits.” Source article here

Researchers from A*STAR Study Follicle Metabolism (1/30/18)

Some interesting research has come out of Singapore’s A*STAR institute led by Thomas Dawson. Dawson and his team believes they have identified a correlation between age-related hair loss and the slowing of metabolism. Different than androgenic alopecia this condition is called ‘chronogenetic alopecia.’ For more please review the source article

Replicel Announces New Asian Partnership (1/25/18)

Replicel has secured a key investment and partnership from the YOFOTO Health Industry Co. of China. YOFOTO will be leading clinical trials for Replicel’s tendon repair (RCT-01) and skin rejuvenation (RCS-01) therapies in China. Shiseido maintains the license to use the hair growth therapy (RCH-01) throughout all of Asia. But it’s good news all around as YOFOTO will provide money for Replicel’s continued development. New partnerships are a good sign for Replicel. Next stop is the that Shiseido data, I’m hoping for the best. 🙂

Fast Track Granted To Alopecia Areata Therapy (1/24/18)

Originally spotted this on HairLossCure100’s twitter page. Concert Pharmaceutical’s therapy for alopecia areata, CTP-543, has been granted fast track designation from the FDA. CTP-543 is an oral JAK inhibitor (ruxolitinib). From what I’ve read, fast track designation encourages early and frequent communications between the FDA and the company during the development process to ensure issues and questions are resolved quickly.

HCell New Company (1/15/18)

Literally jumping right out of the woodwork, the company “HCell” has announced they have been granted an orphan designation from the US FDA for their novel treatment of pediatric alopecia areata. The treatment itself it described as a “topical Injection by regenerating hair through a proprietary blend of commercially procured biologic and autologous tissue.” The company also mentions having a treatment for androgenic alopecia in the works as well. More info to come soon. News release here

Tesla Brush Photos Added (1/5/18)

Before and After photos, as well as commentary from the inventor of the Tesla Brush have been added to the new HairCell article from the main page. 

Calling All Investors (1/4/18)

I am seeking angel investors or venture capitalists that are looking for promising hair growth technology to invest in. Please get in touch with me via the Contact Page.

Hair-Bearing Skin Created In Lab (1/2/18)

Scientists from the Indiana University School of Medicine have for the first time created skin with hair follicles using mice stem cells. Research was led by Professor Karl Koehler. The team was able to grow both the epidermis and dermis layers of skin to create a realistic skin model. An interesting quote from Professor Koehler: “It looks like a little ball of pocket lint that floats around in the culture medium. The skin develops as a spherical cyst and then the hair follicles grow outward in all directions – like dandelion seeds.”

Initially the research was aimed at treating deafness by growing tiny versions of the inner ear in vitro. When the team observed that skin cells were forming as well, they attempted (successfully) to get the skin to grow hair follicles. Full article here.

Skin model created by Koehler et al.

Happy New Year (12/31/17)

A Happy New Year! to all of my readers. I wanted to check in and let everyone know I will not be doing a 2017 recap post which has been a tradition over the past 2 years. I will, however, be doing a 2018 look ahead post very soon. Thank you all for supporting Follicle Thought and I wish you a happy, healthy, and joyful 2018.

HairCell New Website (12/19/17)

I took a look at the new HairCell website and highlighted all of the important factors in my latest feature article. Click the Articles link to check it out.

Japan Hair Blog Article and Efforts for Solidarity (12/29/17)

A very kind and talented hair blogger from Japan, Fuji Maru Kagurazaka, recently contacted me and suggested that the blogs aimed at promoting hair growth treatments/cures for hair loss should unite their efforts and cooperate. While I acknowledge that the websites who are focused on this material are each unique and have their own (and sometimes differing) perspectives, I do believe that civility and solidarity are certainly desirable qualities for this sector.  Fuji wrote up this nice article about my website, check it out (make sure translate is on if you are not fluent in Japanese). And, I encourage you to read his other articles. Fuji has a sincere and highly detailed approach to hair growth blogging. His personality is highly welcomed and refreshing to the online hair community.

Rophe Pharma Used on Eyebrows (12/23/17)

Rophe Pharma has issued a press release detailing the use of Rohpe’s topical hair growth drug on eyebrows. The news ended up on Yahoo. Check the Articles section on Follicle Thought for the full scoop.

Follicum Season’s Greetings (12/21/17)

New article has been posted on the site with information from Follicum’s CBO Gunnar Gardemyr. Details include three topical formulations Follicum is working on for its hair growth drug FOL-005. Check the Articles page on this site.

Kerastem Reports Successful Phase 2 (12/09/17)

Kerastem, a company developing an autologous fat-derived stem cell therapy for hair growth, has reported positive data from their phase 2 trial. The results have come from a 6 month clinical trial involving 70 patients. In this study, the patients received a one-time injection of fat-derived stem cells, and purified fat, into their scalp. Kerastem reports an average increase of 29 hairs per cmfrom the treatment, or an increase of 17% from baseline. The press release does mention that the treatment “successfully stimulates hair growth in people with early stage hair loss”, so that is something to take into consideration when evaluating the results. For more info visit Kerastem’s website

Replicel CEO Expects Clinical Results In 2018 (11/24/17)

Lee Buckler, CEO of Replicel, stated in an interview this week that he expects Shiseido to release clinical trial results in 2018. This is great news that everything is still on track for the anticipated 2018 release of Replicel’s RCH-01 technology in Japan. Lee mentioned “It’s entirely up to Shiseido what they do in regards to this product. There’s certainly a possibility that they could decide if the data is positive, to launch the product in Japan…”. Yes, it seems likely that if the data is positive, Shiseido would go to market with one of the biggest technological breakthroughs of the century. Full interview here

South Korean Researchers Developing Hair Growth Protein (11/21/17) 

Researchers from South Korea have identified a new peptide called PTD-DBM which exhibits wound healing and hair regeneration effects in preclinical studies. The research is being led by Professor Kang-Yell Choi of Yonsei University. Choi’s team identified the peptide PTD-DBM which targets a protein called CXXC5. The interaction of these two proteins leads to stimulation of the Wnt pathway, which then initiates hair follicle neogenesis. Choi hopes to develop this peptide further into a potential hair growth drug candidate. A research paper about these findings was put out by the team earlier this year. Source article about this development here.

SCM Lifescience Working On Hair Growth (11/16/17)

We have yet another biotech research company working on a next-gen hair growth cosmetic product. Their webpage mentions the use of “stem cell culture solution-derived proteins” for hair growth cosmetic products. An imminent release of the product seems unlikely, however it is nice to know how many companies really do want us to have a new product to improve our lives. Website here.

New Article with Quark Pharma WCHR2017 Presentation (11/14/17)

Check the Articles homepage to view an interesting presentation from Quark Pharmaceuticals pertaining to their new siRNA therapy for AGA and chemotherapy induced hair loss.

Please Support Follicle Thought (11/8/17)

I’d like to take this time to formally invite everyone who has found this website to be a useful resource in their daily lives, to make a contribution to my donation page on Patreon.

I know that Follicle Thought has been very useful and inspiring to companies, doctors, and people interested in hair restoration alike. A one-time pledge to my donation page would make a difference in my life and be very appreciated. To make a one-time donation simply click “Become a Patron” on the right sidebar of my Patreon page. Then you can adjust the amount of how much you’d like to contribute; Patreon will call this a “monthly contribution”, however you can cancel your pledge after one month, hence making it a one-time pledge. 😊 I am thankful to all of you who take a moment to visit the page and make a contribution, it means a lot, especially for the hours upon hours I have put into the site to make the best information available to you all.

Stem Cell Company Working On Cosmetic Hair Growth Product (11/7/17) 

A little something for you all to nibble on. I’ve recently discovered a stem cell therapeutic company who has an interest in putting out cosmetic hair growth products. The company, Stemedica, is working on treating a wide range of diseases through clinical stem cell therapies. I counted 6 clinical trials in progress on their pipeline page. Perhaps more interesting for this audience, the company is also developing skin and hair growth cosmetic products from their core stem cell technology. Stemedica has a specific subsidiary in place to roll out dermatology cosmetics called StemCutis. Their website mentions the use of stem cell-derived growth factors to to be used in the products. It’s not clear what stage of development the hair growth product is at, but it’s good to have it listed in Stemedica’s sights

World Congress For Hair Research 2017 (10/31/17)

The annual World Congress for Hair Research kicks off today in Kyoto, Japan. The Congress will go on until Friday November 3, 2017. The purpose of the event is to share presentations about different lines of research and product development regarding alopecia areata, stem cell biology, androgenic alopecia, cosmetic care, wigs, hair transplants, and more. Basically, all things hair industry. At these conferences a few companies typically will announce some news about their developments and progress. I’ll update any news I receive regarding announcements made at the Congress. WCHR2017 website.

JW Pharma, UPenn Collaborate On Hair Growth Therapy (10/30/17)

JW Pharma, a Korean biotech company that specializes in the Wnt pathway, has entered a cooperative agreement with the University of Pennsylvania to development a compound called CWL08006 for hair regeneration purposes. JW Pharma has a pool of Wnt targeting therapies, and apparently CWL08006 makes a great candidate for hair growth. Of course, Dr. George Cotsarelis of UPenn is involved, and the two teams plan to begin preclinical testing by 2019 (I’m a little surprised at that timeline for preclinical). One of the more interesting facets of the report, JW intends “to accelerate its commercialization by launching tests on the human body for cosmetics that utilizes the drug’s mechanism, next year.” If the candidate works well in the cosmetic tests, a version of it could be made available much sooner than the clinical drug pathway, but for now it’s not possible to speculate a time frame for that yet. Good news all in all. 

Deion Celebrates New Hair (10/29/17)

NFL Hall of Fame player Deion Sanders has recently undergone a hair transplant. He has not been shy about discussing it publicly and over the last several weeks has actually continued to put out a slew of hilarious and outrageous posts pertaining to his renewed follicles. For his first announcement to social media, he posted this jubilant and priceless video to his Instagram:

I’ve been looking forward to sharing this with you all. It makes me laugh everytime I watch it. But really, look at how happy he really is and how much joy he feels from restoring his hair. The man is an NFL Hall of Famer, also played MLB, and made millions of dollars throughout his career; and he looks like a kid getting free ice cream on a Friday afternoon because his hair grafts are beginning to sprout. I find it inspiring, to be honest. Keep dreaming, keep believing. We’re all looking forward to having our own “I got some hair!”  moment.

New Company Working On AGA Drug (10/27/17)

A company not previously discussed in online news, SWITCH BIOTECH, has sights on developing a drug for androgenic alopecia. As you will see, the company is still in the very early stages of developing a therapy for AGA, however they are a knowledgeable dermatology-focused company and have a unique method of drug development. Here’s a quote from their website about working on AGA:
“SWITCHBIOTECH intends to develop a drug that either prolongs the hair cycle, stops the miniaturization of the hair follicle, or blocks the signals from the dermal papilla that inhibit hair growth.”

27 Comments on “Updates – Cures For Hair Loss 2018

    • Hi Sonia, unfortunately I haven’t heard of any companies going to market this year.

    • My Reboost review was posted for 2 weeks in the reboost thread before that thread was removed.

      • Hi, I’ve been meaning to ask as I may have missed a post, what was the reason you took down the reboost thread, was it because you don’t have faith in the product claims or something else?

        • But will answer your question here. The simple answer is there was so much negativity that came with the Reboost thread that I decided it was best to take it down, also there was not much evidence coming up that showed impressive or worthwhile results. It possibly could show that in the future, but that will have to happen elsewhere else.

    • Hi DjFresh, I don’t believe there were any, but will look into that over the next few months.

  1. What are your thoughts on Kerastem? Do you have information on possible market release already?

    Best regards,

    Mika

    • I don’t have any information on market release already, I think they’d have to do a phase 3 first. You’d have to get a good look at the quality of results before evaluating the treatment.

  2. Hey!
    What do you think about 2018? Is it possible to get back hair?
    I dont lose a hope but .. it will be disappointing .. if no cure works ; (

    I use minoxidil and saw palmetto – of course minimal result – still waiting for something better
    Greetings

    • It depends on how a few companies pan out such as Shiseido trialing Replicel’s treatment.

  3. Hi,

    Any news on when or if PTD-DBM will be hitting the markets?

    Cheers,
    kingarthur7

    • Hi there,

      To my knowledge this drug is still in preclinical stages so typically it would be around a 5 year wait unless it comes out as a cosmetic product.

  4. Hi Admin,

    Happy new year in advance

    I have a big hope on replicel and Shiseido that it will come this year and I am so excited that 2018 is the year of ending baldness..

    Thanks

  5. I don’t understand why don’t the best scientist across the world team up and help the human race with a proper solution..

  6. Do you think replicel could be available in haircentres as a special procedure in Europe within upcomming 10yrs? To me it seems like for now, we should hold on our follicles until that time, so that they can be regenerated one day.
    Did I understand it correctly that you need to still have hair and the treatment would just correct something within the follicle in order to be dht resistant? So basically it should not grow new hair? I am confused a bit i guess

    • Hi Bunny, yes definitely think that if Replicel’s treatment shows efficacy in Japan it will be in Europe within 10 yrs.

      I think they are aiming at rejuvenating weakened shrinking hair follicles and possibly regrowing some new ones. Their video explains more: https://www.youtube.com/watch?v=cCe5mg7X6zg

  7. So, even if Shiseido trialing Replicel’s treatment was to launch in 2018, the UK or Europe wouldn’t get it for a few years?

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