Weekly Thoughts 1/12/16

Hello everybody,

It’s nice to be back for another installation of Weekly Thoughts. Before we get into the news items I have some news to share in regards to my own hair situation. As I alluded to last month, I have been looking to get an FUE done to restore my hairline and create much more ease in my life. Last week I had an FUE procedure done at Dr. Scott Boden’s office in Wethersfield, CT. Things went well and I will be posting an article about my entire experience later this week. The procedure was around $10K and I opened up a new line of credit to get the surgery done, it was my only choice. I am humbly accepting support from my audience to help pay for my surgery. Many of you appreciate the work I do here at Follicle Thought and if you would be interested in contributing a donation to help me cover the costs of my procedure I would be grateful. Please use the Contact page to get in touch for my Paypal information or mailing address. Thanks very much for your support.

Dr. Christiano Sheds Light on JAK Inhibitors

Dr. Christiano recently did an audio interview about her research on JAK inhibitors for hair growth. The interview covers most of the information we’ve already heard, and also brings forth a few insightful comments from the researcher. The question that everyone still wants to know is if these JAK inhibitors could be useful for common hair loss or androgenic alopecia. Her answer was: maybe. She did say that these JAK drugs were the most efficient thing she has seen for turning on the hair follicle growth cycle in a long time, which is promising.  Dr. Christiano explained that at this point it is necessary for a company with resources to move the JAK research into clinical trials. However, she made it clear that it would be fairly quick and easy to determine whether these JAK drugs were effective for hair growth during initial trials, making them a safer investment. I personally believe that a keen company, perhaps a company like Kythera, will be knocking at her door soon enough to inquire about the JAK inhibitor work. One important tidbit that I picked up from the interview is that apparently the JAK drugs need to be at a high local concentration around the hair follicle to have an effect on it’s growth. This could mean that a topical solution with enhanced permeability would be a great choice for delivery.

Finally, one thing I found interesting during the interview was that the interviewer mentioned that research on using JAK inhibitors for 3D cultured dermal papillae cells was eye opening and that he was very surprised no one was talking about it or mentioned it in the media. Guess he must have missed FollicleThought.com. If you look back to my initial article, the terrific news about Tofacitinib promoting the inductivity of dermal papillae cells was highlighted and the picture of it’s results was shared.

Brian Urlacher Restored His Hair

You might have noticed on your favorite news website or ESPN over the past week, Brian Urlacher had a hair transplant. It looks good. I’m usually not too interested in celebrities getting hair transplants, because ‘hey who cares?’ However, I wanted to include it in this post because I felt that a lot of people might stumble onto this site while searching for information on his transplant. I believe that those people will be quite pleased to come across the information they find on this website.

Shiseido is a Major Player

Most people are aware that Shiseido is big-brothering Replicel’s RCH-01 technology into the Japanese market for expedited approval. Some also know that Shiseido has their own in-house researchers, such as Dr. Manabu Ohyama, who are looking to create hair regeneration through iPS cells. However, up until now I have not heard talk about Shiseido’s research collaboration with Harvard CBRC. It turns out they are working with Dr. David Fisher’s lab as another outlet for hair and skin technology discovery. That’s three major avenues, with the possibility of more that we don’t know about. Be thankful for Shiseido, they have put a lot of focus into solving the thing we all pray for.

Two Additions to the Ultimate Guide

I’ve created two new spots on the Ultimate Guide to Hair Regeneration for the companies Follica and the IBN Singapore. It’s a promising sign that we have 16 entries on the world’s best hair regeneration list.

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