Stemson Therapeutics Raises $15M To Bolster Hair Regeneration Efforts
The company founded on Alexey Terskikh’s hair multiplication research at the Sanford Burnham Prebys Institute has not had a problem raising capital since its inception a few years ago.
In a press release issued today, July, 15, 2021, Stemson Therapeutics announced the closing of a $15 million Series A financing round. DCVC-Bio and Genoa Ventures are two new firms to join the Stemson capital raise, while Abbvie Ventures (Allergan) made a follow-up on their previous investment. This brings Stemson’s tally to $22.5 million raised in the past two years, an eye-catching figure for the hair growth industry.
This round of financing will be applied to advancing Stemson’s cell engineering platform, which involves bioengineered material and will be combined with robotic delivery as a novel solution for hair replacement, according to the release. It appears Stemson has theorized that the placement of its stem cell mixtures within scaffolding will be best handled by robots for precise insertion into scalp tissue. It’s also mentioned that Stemson is currently developing a human skin environment model implanted onto larger animals (likely a pig or miniature pig). This will allow Stemson to test out their implantation processes in an environment as similar to human as possible before starting an official clinical trial. Good stuff.
Finally, Stemson Therapeutics’ Co-Founder and CEO Geoff Hamilton wrote a letter to investors and patients today on the Stemson website. The letter is a heart-felt message of hope and a sincere pledge by Stemson to put forth their greatest effort to effectively cure hair loss. Geoff even mentioned how hair loss affected his late mother during her chemotherapy treatments. A few quotes from the letter:
“..the biotech and pharmaceutical industry have not delivered new solutions nor is the R&D pipeline active in a meaningful way to give people suffering from hair loss the solutions they need. This needs to change.“
“We are well aware the history of false promises, over-hype and failed attempts to develop hair loss solutions. While I cannot yet promise we will succeed, I can project new hope that a serious and highly reputable team of expert scientists, cell biologists, bioengineers, bioinformaticians, biotech executives, biotech investors, and therapeutics developers have come together at Stemson Therapeutics to make an earnest attempt at applying the latest breakthrough technologies in therapeutics to solve hair loss once and for all.”
“To all of you suffering from hair loss and looking for a solution, stay tuned to Stemson Therapeutics.”
Certainly, encouraging words shared by Geoff Hamilton here. We look forward to the next update. Godspeed Stemson.
Posted in Stemson Therapeutics
Very interested.
John Vincent
Author
FT, según tu tabla de las fechas estimadas de comercialización sigues pensando que la solución de Stemson estará disponible en 2027? Y la de TissUse en 2024? Sinceramente creo que el enfoque de TissUse era bueno pero van a hacer muchas pruebas y no creo que lo veamos en esta decada
Alvaro, when posting comments please translate them to English first using a website translator.
I think allo generic hair transplants will come first. getting hair from other people from doctors performing hair transplants. pay Jim and Johny 1000$ for 100 hairs. multiply that by 1000(1 million dollars) and you got a fresh set of hair. all you have to do is blast uv rays to remove dendritic cells so their immune to your body, color and curl pattern match them and your good to go. wigs today are made up of thousands of different peoples hair.
Stemson is cool, its just, their gonna need hundreds of millions of dollars in funding, they know that, and its 10 years away.
Pay $1M for a head of hair? Just flash a few UV rays and get rid of the whole immune rejection response??
I mean, I’m for advancements in all areas but Stemson is much more interesting to me regardless of timeline. There’s always Japan and everything needs time but it also needs to be a practical and attractive approach. Allogeneic could be a very similar timeline as Stemson.
Could you explain why it takes 10 years?
But don’t tell us about failed companies in the past.
Thank you.
It takes 10-15 years because you have to understand. every tissue engineered in a lab has been grown and come out looking extremely artificial to real tissue. what do I mean by this. would you pay 300k for a head of hair that grows in wrong directions. probably not. well thats the state of medicine. we can clone hearts but the muscle tissue will be weak. no point in having a heart that will blow out the first day.
and to follicle thought. I would pay 5 million if it meant I could have my hair back with free fill ups.
in terms of price. you guys think the competition is among us. guy to guy. no its really going to be women to women. I can see women paying 500k to get cloned hair from Stemson so they can finally take off their weaves. and your saying who will pay for this stuff. the same dudes buying thousands of girls g wagons on ig. so if your saying Stemson is gonna be kind and do this from the bottom of their hearts for 40k, yeah no. I dont believe that for a sec. I think they’ll have a 10 year waitlist from women begging to get this done.
but id follow the allogeneic approach because I know what im getting, I know what the other persons hair is gonna look like grown in. with Stemson its up in the air. and they already solved the rejection problem in 2019 so.
I respect your willingness to spend millions on a head of hair, I think all of us would if we had much more than that to spend.
Just curious, why not invest in hair therapies now if you have $5M to spend later on a hair transplant?
I have real estate. like disposable monthly income. I actually thought about paying for trials for allogeneic hair transplants. It’s about 10-25k per person. a 10 person trial. im seriously looking into it.
Interested in discussing more via email AA25?
Joseph, Joseph, Joseph, what happened to that Zen? I saw that post on that other decaying site. Don’t let the knuckleheads get to you…although even Yoda has his moments as we know. Keep up the good work!
Lol Yoda, zen is the intention and sometimes it’s necessary to snatch a fly out of the air with the chopsticks, too. ?
Admin, I appreciate healthy discussion as much as the next guy, but you must realize that AA25 has no idea what he’s talking about right? He’s referencing tissue engineered in a lab and hair’s growing in the wrong direction when the entire point of Stemson is to negate the use of cloned tissue and control the angle of growth by means of the synthetic scaffold they created. To top it all off, they know they need robotics capable of putting this all together to be able to scale the process and offer it at an affordable cost.
I offered to discuss AA25’s idea on an allogeneic transplants but so far he declined.
this wont be cheap, 40k$ is unreal price
Or cut their gonads off with a lightsaber! 🙂
They aren’t engineering tissue, so why are you pretending you understand this process? They’re fostering blank cells within a scaffold (which will also control the direction of growth) and producing new follicles.
This process will be for men and women, but you’re lying to yourself if you think women would dominate the waiting lines. In terms of cost, they already said they have a goal of making it cost around 10-20k. You’re just making things up at this point.
sad thing is companies get tax payers grants then charge ridiculous prices for cures sick world flogging only one log but yet didn’t they study medicine to help humanity for the good of all no its about how much i can get so i can live in candy land sailing in my yacht its all about the stock market not about the goodness of humanity !
When please
One million dollars is quite an investment. One that 99,9% of hairloss sufferers can’t make. Truly viable cure has to something that average working person can afford.
God bless alexey and geoff.
?
Thank you FT for this update I appreciate it!
“We are well aware the history of false promises, over-hype and failed attempts to develop hair loss solutions. While I cannot yet promise we will succeed, I can project new hope that a serious and highly reputable team of expert scientists, cell biologists, bioengineers, bioinformaticians, biotech executives, biotech investors, and therapeutics developers have come together at Stemson Therapeutics to make an earnest attempt at applying the latest breakthrough technologies in therapeutics to solve hair loss once and for all.”
I’m glad they are mentioning over hype and false promises. I trust alexey T
stemson is an extremely competent and serious company. Maybe the only one in the business. I have great confidence in them. If they fail in the end, then at least they did their best. I also have great sympathy for the founders, I think they are really good people. They don’t just see the money, they really see the people behind it. Hopefully they will achieve all of their dreams.
Nomoney great comment!
The founders might be good people but they are 100% in it for the money. They are not gods, they are business people.
I agree Woofy, good to read that he seems to be candid.
Why is AA25 even reading this site’s content. He seems to have it all sussed…
Another poster (Fred) Yoda agrees with. Wow, two in one day! On the internet everyone can be a millionaire. Crap, Yoda is really Jeff Bezos just trying to be one of the boys! 😉
It sounds promising and all, and I believe in their good intentions, but we need to wait for real results
Lol
Regarding the sentiments around Stemson’s ideals and motivations; every business is in it to create value and profit from right? Of course. I think it’s more fair to say that a company intentionally putting out a marginal/useless product is “just in it for the money”. I think Stemson is looking to be commercially successful AND they care about people who want more hair.
of course they also want to earn money, I don’t deny that. But I still think it’s not the main motivation. I believe such people love and live science. They enjoy it and they open up there. They want to combine their passion with making money and I have great respect for that. I think they will carry on with other diseases after their wealth.
Honestly they don’t need to be in it for the money, they can be doing it from the bottom of their hearts. If they make a replicable scalable procedure (robotics allows for that) 40k$ is possible. 40k times the world population over 40yo lol. They’ve achieved endless financial success from the goodness of their hearts. Cancer cure is the same. They come as a set.. financial success and moral victory. Just my opinion. And @AA25 you know they are lying on IG.. thousands? No. Those cornballs don’t even own their own cars much less their girlfriend’s.
Fair enough, I never indicated that I question their well meaning intentions (you saw I agreed with Woofy’s comments on same). However I feel that money is the primary motivator by far (certainly for the investors and most probably for the founders), they wouldn’t be in it if there wasn’t the prospects of a big payday. That’s all, doesn’t mean that they can’t care about hair loss, the two things can be interdependent. And let’s be real…money/investment is more important to lead to success than noble intentions.
Admin…they most likely care if the decision makers are themselves bald and/or family and/or friends are balding. Otherwise its most likely just money and that’s perfectly ok..Regardless of the motivation, the end result counts.
In the end nobody wants competition for themselves in the market place…be it education, appearance etc..
This is not hair related per se but may be indicative of the current possibilities of regenerative medicine:
https://www.forbes.com/sites/williamhaseltine/2021/07/13/the-dawn-of-a-new-era-of-regenerative-medicine-tissue-engineering-comes-of-age/?sh=3a2d3fed7d11
Hi Admin, is there already any news on TH16? I was hoping more news about a release date would come soon.
Peter, I don’t think there will be news until the product actually launches. You can sign up on https://rizn.ca/ for updates.
Brilliant news, FT! I don’t think I’ve ever read such a sincere letter from a CEO. Smart, courageous team of experts doing right by us and pushing our cause in ways we have never seen. Let’s cheer them on people! Baumer, great article! Indeed relevant, and mind-blowing. What truly amazing times we live in. As always, thank you for your wonderful reporting FT.
it looks like the pig trials haven’t started yet
@FT can this be trialled in japan?
I don’t know at this time D1. In the future when I talk to Geoff I will try to ask. There’s definitely a possibility.
Great, now that’s a lotta dollars. Stemson can hire top scientists and fund trials easily with their massive budget.
Thank you admin for the update, and for all the hard work that you do.
Thank you Shayak
Thanks for the update Admin, this is really good news.
Admin, sorry to ask this question here but could you please tell me what is the current status of Moogene Medi with their CRISPR toxicity study required for the FDA?
Have they started the toxicity study study already or have they completed it by now ?
The last article I recall was in November 2020 and it was said human trials would be in approximately 2 years time from the time of the article or from the passing of the toxicity study, I don’t recall the specifics.
I am super excited and interested about Gene Editing Technology being applied to MPB
I’m sorry Sonic, I’m not going to be able to get that update right away. Most likely they have experienced a small delay setback, but are still pushing to get things done. Will have an update by year’s end.
Alright, thanks again.
I think and I’m hoping there will be a lot more competition in the gene editing approach to MPB since the adoption for CRISPR is growing so rapidly. I recently saw an article about astronauts using CRISPR in space for the first time lol.
I also didn’t think there’d be issues with the Toxicity study since CRISPR has been used in humans many times and even for different applications and even cured a rare genetic disease that causes blindness.
If Moogene Medi delays too much they might see stronger competition just like how Breezula now has Kintor on its tail 😉
Yeah D1, Stemson should human trial this in Japan.
Wake me up from the grave if a cure for MPB is ever discovered.
https://www.fiercebiotech.com/biotech/abbvie-backed-stemson-snags-15m-series-a-for-hairy-brush-up-rogaine-propecia
here the CEO says that it will be a few years before they can start the studies. That’s very sad, I thought they would start in 6-12 months.
unfortunately it is a pity, but it looks like it will probably take a decade
I like this comment of Hamilton more than those overly optimistic ones from other companies. A human trial in 2022 is definitely realistic (it was originally planned in 2021).
Terskikh already said in 2020 that a commercialisation will need 3 to 5 years.
They are also ramping up the business executives – so they are working on the business-model too parallel to R&D. So the product will be available quickly after release.
he says quite clearly that studies are still several years away. The studies will therefore not start in 2022.
“ we have a couple of years ahead of us to really try to complete R&D until “
does not say several. in just a couple of years it should be ready for R&D.
“We don’t know when exactly we’ll get into human clinical trials, but we’ve got a couple of years in front of us to really try to complete the R&D to the point where we have confidence and we’ll just have to see how we progress along that timeline,” Hamilton said. The preclinical work is currently being done in animal models that “can very closely approximate the human skin structure and environment,” the CEO said.”
human trials will not start next year, he talks about a few years, moreover, it does not surprise me, they plan to use the robot instead of surgeons, which makes me happy
Sounds like commencement of human clinical trials (3 phases that take many years) are possibly a “couple years” away at best.
yes, that about the robots also makes me happier. This means that you don’t have to train all of the surgeons, you can expand much faster. That will inevitably lower the price faster once 100 clinics offer the procedure. However, it makes me very sad that it will probably take another 5-10 years before the procedure is ready for use. If the studies start in 2024, it will be approved in 2026 at the earliest. In addition, there are the classic delays of 1-3 years. So probably between 2027 and 2030. It’s sad, but still good that they will at least probably be successful.
Nomney 2027-2030 it would be fantastic:) fingers crossed
Also Alexey said in the ISHRS interview with Bradley wolf they are doing the robot so that we will be able to transplant 100,000 follicle transplants if needed and you can’t do that by hand lol.
You guys read way too much into the stemson press release. He is saying 2 years for R&D and mentions no exact timeline when human trials will or if they will start. Cloning hair is extremely tough it seems. They clone organs but hair is more complex since it cycles and stuff. I remember we all were throwing out random timelines for tsuji…2, 4 , 5 years for release and we saw what happened with that. Let Aleksey develop his R&D and I am sure in two years he will give us another new timeline for when they start thr pig trials. Once pig trials are done he will give us human trial start dates if it works. If I were to give a guess, I would say human trials to start in 2028 to 2030. Then if all goes well 2035 to 2040 where they will roll this technology out where its available to the masses. I know it sounds so far away but it really isn’t for medical science advances and how slow things move to get adopted. If anyone has a chance of bringing this out I would say aleksy would be the guy. He seems like a smart and respectful dude.
Mjones :”The preclinical work is currently being done in animal models that “can very closely approximate the human skin structure and environment,” the CEO said.”
i can wait till 2040 anyway no problem with that
What a ridiculous posting.
15 years for commercialization?
Lol. ABSOLUTELY NOBODY would invest in such a timeline.
Sure they would Ben, your post is naive. If they can show early compelling scientific data and can make the business case ($$$) there are investors that would get on-board. How do you think most biotech’s get funding? Drugs and devices don’t happen overnight, it’s something I know a bit about 1st hand. It’s a long term proposition.
I would agree that investors like the group from UK are not interested in a 15 yr timeline, can’t imagine that Stemson proposed to them a confidential deck that said “We aim to commercialize in 15 yrs.” Institutions like Allergan/Abbvie have a little more leeway to invest in longer term plans because they’re going to be doing aesthetic biotech in 15 yrs one way or another.
I’m disappointed a couple of more years in preclinical. Pig trials will happen soon should happen within the “couple of years” timeline before human trials. I don’t think 2028 for human trials that’s a bit dramatic in my opinion but who knows.
According to this interview (last year), 3 to 4 years of animal experiments prior to being able to start human trials. If nothing’s changed since then, 2 to 3 more years prior to starting human trials.
https://www.youtube.com/watch?v=t5trLFA0S-c&t=1323s
Honestly screw it id rather have a full head of hair in 20 years than never lets just see how this all pans out
i don’t feel like chilling in these forums for another 10 years. I let ht delete me. Will ignore these issues again. With this financing I thought that stemson could be ready in 1-3 years, but they will (understandably) need at least another 5 years. This is not healthy for me. All the best to you
I get that nomoney, you seem like a good poster and hope you stick around. People on these forums get way too vested in these various treatments. It’s good to have realistic hope however hair loss is a complicated issue. I’ve seen it again and again where readers elevate these companies and researchers to an almost god like status…see Tsjui or even this press release. Hang on every word that’s reported (see Youngjet). Like in this article, a Guy says a few kind words about hair loss suffers, admits their path is not an100% slam dunk and people think it’s the second coming. Sorry about the tough love guys and Yoda not blowing sunshine up asses. Yes this is something to be excited about and hopefully look forward to in a realistic time frame but keep grounded in reality.
Hey admin are you blocking my posts. If so, all good, your site your rules….I posted twice and they arent loading up…wondering if it’s my side the issue or if you have me blocked.
Wait admin lol now I see them. Strange had to use another browser.:)
That happens to me sometimes too MJ. I think that the Admin has had enough of Yoda’s babbling but then a few hours later the posts appear. Possibly there are some key words that put the post into “moderation”?
There are multiple filters that sometimes put posts into moderation. There are a few key words that I set up, and there is an intrinsic WordPress filter which will put a temporary hold on a post which contains multiple links (typically bot spam posts are filled with links). I’ve also seen longer posts from real users with only 1 link sometimes show up in moderation, I guess they resemble the typical bot-produced spam post. And then there is the occasional post that gets manually deleted if it contains repetitive themes that detract from the conversation. ?
Hey Admin, what has transpired with that Ostrich egg concoction some readers were excited about? I think you were putting a section up for posters to relay their experience. I’m having a tough time finding it, is it still active?
This is the post https://folliclethought.com/ostrigrow-before-after-photos-plus-discussion/
Thank you Jose, how did you navigate to that page on the site? I’ve clicked all the buttons at the top and can’t seem to get there, HOME ADVICE CONTACT ARTICLES UPDATES. Had this challenge before finding a product review for shampoo. Is it Yoda or is these sorts of things hard to find?
There’s a link to it in the Updates thread I believe, but I didn’t make a main article for OstriGrow because it’s an unproven product. I wanted to have a place to discuss it slightly low-key. Adding it to favorites in browser can keep it handy.
Haha so true Yoda:) I was like did the admin break up with me hahaha. I was like…naaah…he’s my boy lol
Thanks Admin, I agree with your sentiments about OstriGrow. I find it to be a tough story to believe in. Nevertheless it popped into my brain and wanted to see if there was any feedback yet.
there’s another drug called Ranibizumab like veterporfin. Maybe it wound heal scars in mice as well idk. And It’s already FDA approved
I’ve given it some thought and I’m going to step away for awhile as well like nomoney but It will be temporary. Reading this stuff when it’s not even available to us is hard on my mental health. I want to make it clear It’s not you FT it’s me. You do a great job! So take care yoda, mjones and FT! Veterporfin will hopefully change the industry! 🙂 see ya guys!
On another note, I inquired with Cassiopea about the availability of Winlevi in the U.S. Here’s the reply:
July 07, 2021
Dear Jon Ness:
Thank you for your recent inquiry about WINLEVI® (clascoterone). You requested information regarding:
When will Winlevi be available for prescription in the United States?
Winlevi will be available in the US market by prescription only in Fall 2021.
If you have questions regarding any of the information we have provided, you may wish to contact your healthcare provider. Enclosed please find the package insert for the full prescribing information.
Hello everyone! I know this is out of topic but i recently came across a dna test from fagron called TrichoTest. With this test you can check many parameters and how you are genetically ‘programmed’ to respond to different treatments. Basically you get a personalized treatment plan. I came across this test because i was looking for a minoxidil response test (my SULT1 enzyme activity).I find it pretty interesting and i haven’t seen like any posts about it on forums. admin i will really like to know your opinion on this.
Rise technology also doing a survey like Mane biotech
No further news ,when time goes without any advance hopes are thinning
Hey,
I am new here, just joined the community couple of days ago and maybe I don’t quite catch the point although in my opinion that’s an awesome news. When a company raises $15M they definitely have something big. No one would invest that amount in vain. And maybe that’s not around the corner but as I got it will definitely be available in 10 years or so. We just have to be happy that this issue raises attention and scientists along with business people start working on it.
BTW, @Woofy97 good luck. Hopefully, I’ll see you soon back. Your comments seemed very compelling.
Hopes up!!!
Any update from Hairclone due?
I have a feeling that they will not be offering their injections in 2021…
Hair follicle banking is already available via our clinical partners. Using these hairs to achieve hair rejuvenation will hopefully be in 2022.
The last comment that i get from hairclone.
Yes it appears their schedule has been pushed back to 2022. A bit of shame I suppose, but England was slow on the reopening front. I look forward to their case studies in 2022.
Hi admin, what about th16 and th07 from triplehair? When we will be able to buy this ?
Triple Hair says July (this month) on FB now for their “16” product. Don’t hold your breath….they’ve missed timelines before.
Hi
what happened everyone? No news even some bad news will do
Feel free to jump in and interact with others Kapil.
What happened to insilico. TheAI
He is very active in social media but no mention of any research
Do you remember name of the company use blackmole hair molecules spray?
Man most of this stuff mentioned is a blur to Yoda. Here’s to you guys to remembering all of these potential treatments and to the Admin for keeping it all straight!
Insilico will likely be quiet until the phase 1 trial is completed, they may have a partner involved and have a requirement to be quiet about things.
The hairy nevus company is Amplifica. They are also working behind the scenes.
I guess Amplifica is underground like a “mole”! 🙂 Crap, that was like a dad joke!
@admin, we are in for a surprise then? 🙂
Hi admin, do you know if Kintor is working on bringing pyrilutamide to european market? I have only heard about US and China. And if this pyrilutamide will be approved in china but not in EU can I still buy it on chinese market and ship it to europe?
Cart way before the horse, still a few years away if it comes to fruition. If so, you’d imagine they’d get EU approval if going for FDA.
I wonder how latest protein folding computation breakthrough could accelerate discovery of baldness cure. If someone has a link to article regarding this topic, please let me know
@kolos , New technology takes time to adapt, so it will take a lot of time before scientist can use the EMBL database and do significant research.
Someboby has received an email from RIZN regarding launching day for TH16? Tks!
seems that TH16 will be released this Friday – it will be pills (vitamins) + spray for hair density
Yes but only avalaible in Canada and in the US at the moment.
Hi, everyone!
How much should Rizn cost! And when is it possible to sell to Europe? Thank you
@Admin, a page for TH-16 before/after photos would be very much appreciated!!
I will get that going for you Anthony, just going to decide if it should be a new published article.
Hi Everyone
Have you heard about CRISPR used for Gene Editing Therapy?
It’s personally my favorite for the possible cure against male pattern baldness.
If you’re not very familiar with CRISPR, or even if you are, I strongly advise you watch the short Netflix docu-series called “Unnatural Selection”.
It is brilliant and it’s done by a guy who has a PhD and also worked for NASA.
They have already done things like regrow limbs in insects, merge characteristics of different living creatures, like taking the DNA that makes a firefly glow and injecting it into a mouse/rat and it became a glow in the dark mouse.
In the first episode of Unnatural Selection you will see how they used CRISPR to inject DNA found in the stem cell and embryo of mice into mice which were very old, towards the end of their life, hunch-backed (spinal bent just like how old humans sometimes get hunched-backs), slow moving/mobility deteriorated, their hair/coat looking old, etc
The result, was the mice that were injected with the DNA found in the embryo of mice, turned into a much more youthful mouse, NO hunch back, restored mobility to youthful days, sheek and young looking hair/coat, and it was said that the life span of the mouse was extended by approximately 30%.
Which is massive!
Basically the cells in the mouse were restored to a younger state, making it far more youthful. It was amazing. Like drinking from the fountain of youth.
Heck if their able to do that to humans in some way they might not even need to know the exact molecule signals to turn on and off to target male pattern baldness specifically.
But of course people would also
still like to find the exact signals to turn on and off.
The only thing slowing down the Gene Editing technology was ethic boards who were resistant to changes been made in humans via Gene Editing Therapy.
When Engineering things, especially genes, you need to start with the smallest change that would produce a favorable result and then scale up, for that reason the treatment was delayed and first started on mice and other plants/animals before moving to humans.
The fact that they used CRISPR in vivo* recently is massive and the fact that it cured a rare genetic optical disease is even more amazing.
It definitely means a lot more is to come from CRISPR in terms of in vivo applications with restrictions starting to lighten slowly. Its a huge move in the right direction.
Even NASA scientists recently used CRISPR in space* very recently for the first time.
The great thing about CRISPR is that is so easily accessible, usable and cheap that it’s being used by a lot of people recently and also that means it’s being used in a variety of applications not just Cancer or a few diseases.
Also, Moogene Medi is one of the first Gene Editing companies that is already working on using CRISPR to treat Male Patterned Balding. It is doing this alongside trying to separately use CRISPR to treat Colon Cancer. Yes they are working on both diseases at one company simultaneously, just like many other companies will hopefully also start to do.
I know that Gene Editing Therapy is already being used on many different diseases like It’s being used for people with many cancers, sickle cell anemia (40+ people cured from the trials to date), cystic fibrosis and many more to come in the short-term.
It’s being used to treat the #1 genetic deficiency in the US, hemochromatosis.
And they’ve even found more tools passed Cas-9 such as Cas-13
I really hope we see a lot more CRISPR based approaches to tackling Male Patterned Balding ?
@sonic, AND my question to you is, which gene is responsible for AGA, is there only a single gene which is responsible or there are multiple genes involved?? The answer to the first question is we don’t know, and the answer to the second question is no, there are multiple genes and multiple locii involved. In SMA(spinal muscular atrophy) and sickle cell disease there is a defect in single gene that too a fault in Just single base pairing. So your theory of CRISPER editing to a full head of hair is limited as of yet.
1) Did I say that only one gene is required to be turned on and off for combating male pattern Balding?? No.
2) It’s not my theory, as if I invented Gene Editing Therapy LOL.
Gene Editing Therapy is one of the most revolutionary technological discoveries we’ve made as humans. The technology is still relatively in its infancy having only recently been around but it won’t take you long to research just how much it is daily being used and improved.
I did not say it would happen immediately but I do believe soon before 2030 we will see some type of gene based treatments come into the market for combating Gene Editing Therapy.
The purpose of me speaking about Gene Editing Therapy is to create awareness which is what this website is for. Many people do not know what it is and I provided knowledge of it.
Imagine thinking just because Tsuji or Stemson for example doesn’t have the technology now to treat MPB that meas they never would. LOL, even Stemson and Tsuji are still in R&D phase.
Have patience just like you are for other technologies.
Furthermore, the admin of this website already posted an article about Gene Editing Therapy being used to treat MPB by a company called Moogene Medi
Lol , i know what moogene is doing, they are not using crisper in the way you are taking about. And i know in future we might have a solution to that, that’s why i said it is limited as of yet. What will you do with the solution if you don’t know what the problem is or where the problem is.
I only mentioned Moogene Medi because it is the first Gene Editing company that I am aware of that is using CRISPR to treat MPB. Moogene Medi is only the beginning.
Regarding which genes/molecules signals to turn on and off, I don’t doubt that people will eventually figure it out in time. Although as I said earlier, it may not even be necessary to know exactly which Genesee to turn on and off to target hair specifically.
They possibly may only need to return the cells to a younger state/re-activate a growth/development stage.
This was already done in mice in the first episode of the Netflix docu-series by scientists when they injected an old hunch-backed mouse with the DNA found in the stem cells and embryo of mice. The result was that the mouse was brought back to a more youthful state, with no hunch-back, Mobility as if if we’re youthful, it’s hair looked like it was of a young mouse again and it was said that the life-span of the mouse was extended by approximately 30%.
If something similar can be done in humans in the future, that would render the need for knowing the specific signals required for controlling hair growth in humans and preventing hairloss.
I don’t have all the answers as yet to the specifics but I know the potential room for growth/advancing of this technology for Gene Editing Therapy is incredible.
Kintor’s GT20029 phase 1 trial update https://folliclethought.com/updates/
Thanks for the update Admin! Great news! At this speed we might even see Pyrilutamide released end of 2022 and GT20029 released end of 2023 in China lol.
I’ve also just received an email from Triple Hair (RIZN) saying their finally launching their TH16 (Therapy 16) on July 30th at 12pm EDT.
Shipping will be available in the US and Canada.
Not sure about price as yet strangely.
Also it seems that TH-16 is a topical spray, and they also have oral tablets called “RIZN Complex”.
It can be purchased together (TH16 and RIZN complex).
I was not aware of this before. Hopefully it’s not expensive.
Looking forward to the reviews on Triple Hair/RIZN from the community.
Hello guys!
I require a bit assistance. I am 21 years old and suffering from diffused type of thinning since late 18 years. I have taken 3 sessions of prp and I am on finasteride since July 2020. It’s been over a year now but I haven’t seen significant effects from it. There are periods of around 1 week when my hairfall almost completely stops but then starts again. Now my question, is 1 year not enough? should I continue taking finasteride or look for any other option such as dut or something? Is anyone here who has seen results from finasteride after 1 year or some time?
Any response will be appreciated though I am not in favour of using minox.
Yoda will be short and to the point Kay, carryon with Fin, drop PRP and start Minox. PRP can cause shedding and my experience plus with what I read it has a very limited chance of having an appreciable positive effect. You need a growth stimulator, Minox is the best we have that’s readily available. No legitimate reason not to get on it topically at this point.
Hi Kay,
Honestly I’m not a fan of Finasteride for many reasons, many of which are the side effects of Finasteride. If you hadn’t gotten any side effects from Finasteride then you could probably continue using it unless it’s made your hair worse in your opinion. Finasteride should have peak results at the 1 year mark so you should be getting a fair result of what you should be doing going forward regarding it.
With dutasteride, I’ve heard a lot of mixed reviews but mainly that DUT Made things worse for people. Lots of people also complaining about the side effects of DUT.
As for Minoxidil, most people will tell you it’s almost never grown any cosmetically significant hairs.
You might want to try Triple Hair/RIZN new hair treatments that will be released on July 30th. Read my previous comment where I speak about it.
They claim to have had better results than both Finasteride and Minoxidil, and WITHOUT the side effects.
@sonic ,” As for Minoxidil, most people will tell you it’s almost never grown any cosmetically significant hairs.” What?? Minox is probably the only thing available right now that grows some hair, fin also does but to a lesser extent. Moreover you are suggesting a newbie in the MPB world a product which is not proven in the market yet. Follicle thought is the only sane website out there which provides genuine information , and let’s keep it like that.
Like I said, “most” people would tell you Minoxidil has almost never grown any cosmetically significant hairs. You are one of the few people who might have noticed Minoxidil working for you but even the admin of this website himself mentioned the same thing in the comments section of other posts on this website, so lol no I will comment. It’s also very widely known that Minoxidil has almost negligible effects.
Furthermore, FYI, the admin of this website was the one to first mention Triple Hair with updates and articles. Maybe do some research before you talk?
Nothing is wrong with advising someone with hairloss to try possibly the most promising treatment we have that isn’t a surgery. Also, it’s a natural product so no side effects. Much less to use than trying Minoxidil and fin/DUT which has potential side effects for many.
So no, I will advise.
From do you get this “most” stat?? From your own experience? Minoxidil follow all or none principal either it works for you or it doesn’t, and if you are not someone who is in the late stage of baldness it does usually work. But if you are someone who don’t have that sulfotrasferse enzyme(i think i remember it correctly) then unfortunately you will be a non responder. Moreover i don’t have any problem with you giving advice, its a public website you can do whatever you want , but telling bs about a FDA approved proven treatment just to promote a treatment you are excited about is not okay. Am i saying he shouldn’t try th16? Heck no he absolutely should, but not because of the fact minox have negligible effect.Triple hair might be revolutionary path breaking treatment ( i hope that it is) but its not proven yet in the real world. Kay is a young MPB sufferer and he has evey right to get the information. AND FYI admin doesn’t endorse any product like you which isn’t proven in the world yet, he does a noble job providing correct information about ongoing research on hair regrowth and AGA treatment, and gives his opinion on it. Cheers!
If you spend some time on every major hair loss forum in the internet you will find that almost everyone says that Minoxidil gives negligible results. This is not just coming from my personal experience using Minoxidil, although yes even when I used Minoxidil at best I had some vellus hairs growing which weren’t cosmetically significant.
There’s many reasons I don’t blindly believe studies 100%. Some of which are the fact that we’ve had FDA approved studies which make it seem as if the efficacy is really high and the side effects are so low/almost negligible which is the furthest thing from the truth as future/later studies proved initial/early studies to be wrong.
There are loads of studies coming out saying how even Finasteride even though FDA approved has a lot of side effects and affects far more people than before. Previously, around the time when Propecia was first released, Google itself was just created. Barely anyone had the internet around 1999 to report side effects. Online hairloss help/support forums started many years after Propecia’s release and larger numbers of independent studies where done many years after that. Nowadays there are dozens of studies proving the harmful effects of Propecia with even medical doctors who are verified on Twitter even tweeted to other doctors about the side effects of it.
There’s a lot of secretly funded studies around, to make certain treatments look far better than it is. Fortunately, recently a lot more studies have come out proving how harmful even FDA approved treatments are.
Regarding TH16, let’s not pretend like the admin here only provides updates of possible treatments with zero hopes that anyone of his readers tried the treatments when they become available. The admin has several times asked people what there results are after some hairloss treatments in the past were released. Most if not all were unsuccessful but he then only advises against it. However, initially he would want people (his readers) to try the treatments (ofcourse not medical advice he’s giving) because how else would he find out quickly the results and tell the FT community to stay away from the treatment or not.
Everyone has their own choice whether they’d like to try a new treatment or not. My job is to cover promising developments and subjects that readers ask about. There’s always going to be people who want to try a new product with legitimate background when they’re announced. People will naturally share their experiences.
Exactly. Even I’d like to try TH16.
I got feedback from Triple Hair (RIZN) saying that prices will be displayed tomorrow Friday 30th July at 12pm EDT on their RIZN website
True dat Shayak!
It’s fine that people want to try and new product, I’m all for it as long as they are realistic. What I have a problem with is someone crapping all over medical treatments that are proven to work, making false statements because they’ve read it on the internet on other “major hair loss forums”. WTF does that even mean? It’s the hair loss equivalent of saying the moon landing was fake, the earth is flat, etc. because you read it on the internet.
Sonic, just because you supposedly got side effects from fin doesn’t mean that everyone will. The data supports the opposite, I am living proof but that doesn’t mean no one will. Your statement on minoxidil is factually inaccurate, guess you take the comments you read on the internet as iron clad facts. Instead of using treatments that are FDA approved with a long track record you’re recommending a cosmetic product that just hit the market… really? ROFLMAO
Yoda, firstly, I didn’t say FDA approved products like Finasteride wouldn’t work on every single person and I also didn’t say that every single person who uses it will get side effects, but many people do get side effects and for many people it doesn’t work and only makes things worse. I don’t simply take the comments I see online as concrete proof, rather they re-affirm my suspicions after I see a large amount of people also complaining of the product. That’s just the start though. I then go by studies which have been released to further confirm these suspicions. If you would like, I can send you links of DOZENS* of new studies regarding the side effects of Finasteride and how much more people it affects than Merck/other online sources claim didn’t as “facts”.
Also, just because Finasteride/Minoxidil worked for you Yoda and other people, doesn’t mean it would work for everyone and not have side effects.
Here a concept for you Yoda. If it weren’t for major online forums, companies would make almost magical statements about their products, we see it happen in any industry, false advertising how good something is, until people form online forums and write about their real experiences with the product. Are you saying we shouldn’t believe any of he people in online forums just because that’s where the information was found?
Definitely doesn’t sound like a good idea.
If you’re searching for a product, company or service, let’s not pretend like people don’t search for the online reviews of what actual people* who tried it have to say, and not just possibly paid articles and paid “independent studies”. LOL
And as I said, there are now Dozens of studies saying negative things about Finasteride. It’s also no surprise that almost every company in the pipeline also mentions providing a treatment without the side effects of Finasteride or Propecia with Better Efficacy as a selling point. If these side effects and low efficacy of Finasteride and Minoxidil were not true, these companies wouldn’t be saying this and you and many other people wouldn’t be on these forums/web sites if Minoxidil and Finasteride weren’t as good as you claim LOL.
Even Kay mentioned Finasteride seemed to have made the hairloss worse after 1 year of trying and the weak excuse someone had was “maybe it would have been worse if you weren’t on Finasteride” LOL.
Sonic, you certainly aren’t constrained by reality as you create your own and do your best to convince others that it’s the truth. This seems to be important to you to convince others on your perspective on FDA approved medical treatments. Have at it, you win, Yoda out! 🙂
Yoda…Sonic aka Sonic Boom wrote 2 days ago on the German forum that he is contemplating using Finasteride in 2023.
He also does not understand the concept of confirmation bias and statistical sampling.
Madness on social media
MRKA, I don’t know what you’re talking about because you replied to my message and then said Sonic aka Sonic Boom. Firstly, my username on other hairloss forums doesn’t even have the name “Sonic” in it.
Secondly, I’m not German so I wouldn’t be on a German forum, Thirdly, I never mentioned I was contemplating using Finasteride let alone using it in 2023, especially when I’ve already used it for 2 years in 2016-2017 and would never touch it again.
Maybe you are fooled by confirmation bias but I am not. As I said, I have DOZENS of real studies proving what I said about Finasteride. Also have screenshots of verified doctors on Twitter also talking to other verified doctors on Twitter where they are discussing how real and common the side effects of Finasteride is.
You calling the fact that I have proof of multiple sources + studies + an huge amount of normal people who have tried Finasteride and all said the same thing about how bad Finasteride can be “confirmation bias” is the most ludicrous statement I’ve heard. It a really weak excuse from pro-Finasteride people.
You’re essentially saying because I have proof from various verified sources and and studies it’s now “confirmation bias” LOL. NO. IT’S CONFIRMATION there’s evidently a lot more wrong with Finasteride that Pro-Finasteride people would like to admit and try their best to cover the cracks.
Your assumptions about the sampling of the studies are also wrong.
Ok, one more comment…I can find sources that the moon landing was fake, the earth is flat, the Sandy Hook murder of babies was a false flag operation, CV19 is fake…does this mean that these are true statements?
Yoda, The very fact that you tried to compare professional scientific studies stating how bad Finasteride is with sources that the earth is flat tells me all I need to know about your comments and level of thinking. As for Covid-19, there’s been a lot of crazy theories, most of which don’t come from verified and medical professionals/doctors.
Your attempt at making it seem as if anything bad said about Finasteride is shamefully weak and just shows how much you are reaching to hope to convince people there’s nothing to be worried about.
As I said earlier, even most of the main treatments in the hairloss pipeline compare their treatments to not having the side effects of Finasteride and to be better in efficacy as their selling point for a reason.
Simply, if Finasteride or even Minoxidil was even remotely as effective as pro-Finasteride people would like everyone to believe, there would be almost no bald/Balding people and there would be mostly people with good heads of hairs, and just looking around at the people you know or see on TV, or on the internet, your community/country, it’s very easy to tell that’s the furthest thing from the truth.
Propecia has been around for 2 decades, Minoxidil for longer. Anyone experiencing hairloss has heard to these two, and either tried it or didn’t due to potential side effects. And those who tried it, well, if it were nearly as good as it is, it would be displayed on TV, the news, Billboards all the time about an amazing breakthrough. However, it is not, for a reason.
It’s really quite simple logic.
I just want to share my experience so that someone considering minox doesn’t give up after your comment. It worked so well for me that I’m actually upset because it revived my hair loss anxiety. I feel like I’m living a lie lol because I know in a year or so my hair will dwindle. The “I told you you weren’t balding” talk has also increased again lol. But I’m enjoying it for now and grateful. Also it took ~7 months to see ANYTHING. I think I did have some chest related sides at first that went away. It was almost a muscular feeling so I wasn’t too worried.
To agree with you on something, I had terrible sides with literally 3 doses of saw palmetto and it persisted for like a month after. For that reason I would never try fin and I personally tell my friends not to use it. I think the mechanism is bad for some people. I have my theory that it’s people with physical builds like me that need to avoid it. I have a stockier friend that uses it and he’s fine, I still tried to sway him away, but he’s fine as far as I know.
This is all 100% my opinion and experience.
Yes i agree. Blocking DHT is asking for trouble.
Finasteride reduces DHT in the body systemically. Blocking DHT systemically causes loads of problems.
Using Finasteride is like a woman blocking most of her estrogen and increasing testosterone a bit too. Obviously blocking the gender specific sex hormone is going to have some sort of ramifications. To what degree is going to be individual though, and it doesn’t surprise me that so many men report a lot of side effects after blocking more than 70% of their DHT for a long time (and also increasing E).
Yes, “logic”…apparently Yoda has been schooled by coherent, logical data having to do with comments on websites, lack of advertising campaigns for readily available cheap generic meds, that if current treatments aren’t 100% effective and that fact that new treatments are being developed ! 😉 Yoda isn’t trying to convince anyone of anything, just trying to cut through all of the “logic”.
I know Admin hates these back and forths but you gotta admit the Sonic and Yoda show is good entertainment! 🙂
*Admin Please excuse my last two identical posts of this following response of mine, I made a slight typographical error but I corrected it below*:
Yoda, it seems you love to forget I have DOZENS of real professional studies done on Propecia/Finasteride and not just comments found on websites to back up what I’m saying. I’d be more than happy to share them with you privately, I respect the Admins comment section so I won’t post them here as there would be more proof of Studies of how bad Finasteride is than there are comments about this post of Stemson Therepeuctics lol.
Also, yes Propecia was made low cost but in 2010 Merck made $447 million in sales for Propecia, so let’s not pretend like they didn’t have the money to make those false claims via better advertising like they love to mention. They probably use that money to secretly fund so called “independent studies” or paid website reviews to make it seem as if Finasteride/propecia is more authentic/better than it is LOL. Fortunately, as time goes, Propecia/Finasterides 15 year head-start that they had to post all the propaganda they want is starting to change as people and communities, scientists, medical professionals, verified medical doctors on Twitter even are all starting to speak out about the negatives about Finasteride. Not to mention how most companies in the pipeline that we all support are also pointing out the side effects and low efficacy of Finasteride as a major selling point.
It’s become pretty obvious that there must have been a lot of things wrong with Finasteride. I’ll take the win on this one Yoda ?
Sure, I’d love to have a guys like you sharing things with me privately, that’d be freakin awesome Sonic (that was sarcasm). I was thinking about it, indirectly fin is advertised by companies (here in the US) like Roman and Keeps, just in the past few years. These companies aren’t run out of some guys basement, they have big time investors. Do you think the pitch was “let’s get into a business where the majority of our customers get side effects, are unhappy with the results and we have little to no customer retention”? “Winning” seems to be important to you Sonic. Yoda just wants you to be happy. XOXOXO
Yoda, of course Finasteride/Propecia would have had advertising, my point is that if it were even half as effective as pro-Finasteride people claim it is, it would be regularly advertised all over the news, TV, media, website but what happens is that nowadays you get almost an equal amount of people in the media mention the side effects, maybe that’s a big reason they don’t make those claims on TV or large scale media anymore. Especially with the low efficacy.
And it’s not about winning, but I rather only mentioned winning because if you recall correctly, your first message to me on this debate was “you win” 😉
For me it’s about spreading awareness about the truth the help others not get harmed 🙂
No hate against you Yoda 🙂 Would want to see you happy too with lots of hair 😉
Hi Kay,
First the golden rule, always use prescription medicines under medical supervision.
I understand you are not satisfied with your results. Does that mean your balding progressed or regrowth has been not satisfactory?
The problem is that you don’t know the counterfactual scenario. Without Finasteride and minoxidil your balding may have progressed significantly in the past year. Maybe your treatment therefore is successful…who knows.
It is possibly true that the majority of users do not respond to topical minoxidil.
There is some evidence that microneedling enhances minoxidil response. Refer to a 2020 study from Sharma etc. You can read it for free.
You may also want to look into oral minoxidil (under medical supervision).
We all hope that TH16 won’t be snake oil.
Two years ago, Celino released a product in Korea. Admin also reported on this product. It turned out to be ineffective as fas as I can tell
Its good to be positive about TH16. In one year we probably know if its effective or just another NGF574. Until that day you may want to contemplate to continue with your existing treatment( assuming you have no side effects)
Never ever start with an unproven treatment and stopping with a proven treatment. This should be obvious.
For credible information you may want to visit the NHS website.
Be extremely careful with information on social media. Only use ‘controlled and approved data’..as we say in my profession.
After all, you would use the ‘Financial Times’ for information on investing and financial information and not channels like ‘mission money’ on YT…lol.
Is anyone going to try RIZN? I’m somewhat disheartened that they’ve included a “multivitamin/mineral” component to their spray product… Nevertheless if we have anyone willing to give it a shot for 3 months we’ll have more info quite quickly…
A “multivitamin/mineral” companion product as part of a package for a cosmetic product is something to note Anthony. We’ve seen this movie many times before, maybe this one will have a different ending. Not something that I’d put my $$$ on the table to try, wishing anyone who does the best of luck!
Hey, I’m part of the Ostrigrow free trial.
After one bottle (one month) here are my results:
Crown: https://ibb.co/G0mJFx2
Crown Close: https://ibb.co/fvRMn6J
Front: https://ibb.co/DtX3KF0
I have no side effects. I posted a little more about the pictures on the discussion page. Admin, if you can replace the original pictures I shared with these updated pictures that would be appreciated. Thanks guys.
Thanks for the update Toccata, I know you are going into this with your eyes wide open, will be good to learn what your experience is.
@sonic “They possibly may only need to return the cells to a younger state/re-activate a growth/development stage.”, Congratulations someone is listening , @ turn biotechnology and possibly david Sinclair. I hope they become successful, turn seem to be very confident about their pre clinical data.
@Shayak yes I really do hope turn biotechnology and David Sinclair are successful 🙂
Hey Admin, any news on Hairclone and Follica? Are they still looking to release their injections and RAIN(respectively) this year??
Thanks
HairClone appears to have hit another setback due to restrictions over the past year, unfortunately injections are no longer scheduled to become available this year. I will share on the Updates page officially soon. Follica has yet to begin their pivotal trial, there’s no chance for release in 2021. They may be re-evaluating their strategy due to having a limited innovation in their technique (minox + proprietary needler).
Hey Yoda…lets hope this movie has a happy end!
But it feels like that it has an ending similar to ‘Westfront 1918’
Ya know MRKA, Yoda does dispense advice. I tell readers what’s worked for me and to always consult a (knowledgeable) doctor when considering Fin, Dut. I have never said, “you should take fin, you won’t have side effects”. This would be the reverse equivalent of what was recently posted in this thread, then that person back peddled. Yes, we all want a “happy ending” in more ways than one! 😉
Thanks for the quick response, as always release dates pushed back, can never catch a break.
True, but for good measure I feel obligated to point out that Hairclone offered an equity crowdfunding campaign (not simply asking for donations) to the hair seeking community in 2018 and they were left hanging. If they had reached their modest goal of ~$300k, I can’t remember the figure exactly, they would certainly already been offering injections in the UK. Minimum investment was around $130 USD. It could have easily been funded.
I cannot help but feel that Hairclone’s funding strategy was poorly advertised – had it been promoted through more viral channels with better incentives (say, a kickstarter where your funding contributes to your operation), I certainly would have donated, and would donate again. I’m sure plenty of other people would too. Perhaps worth gently relaying to Paul…
Thanks for the feedback Norwood, for what it’s worth, I think they could have done a better job with promoting the campaign, too. I was just amazed at some backlash they received by people who hang out on hair forums, but that’s another story. Though, I don’t think there’s a much better incentive than saying “you can help get this out to reality soon.” I also have brought up the idea to Paul about running another campaign and they’re not into it as they invested a bit of money to get the campaign done and it did not bear fruit.
Could you comment on the development of a new drug for alopecia from omega therapeutics?
Hi Rodriguez, yes thanks I’ve noticed the company and will include them in an article or Update soon. So far, there is not a lot of information available and they are a publicly traded company so they will not give interviews.
@admin, waiting for a new article on this from you, went to the link shared by @Rodriguez, the technology of omega therapeutics seems to be similar to Turn, using mRNA to modify the epigenetics, and control gene expression ( but their diffence in their approach). They are targeting a single gene SFRP1(if i am not wrong) the same gene which was found to be downregulated in the cyclosporine A study from the University of Manchester . They seem to have studied it and with the help of their own machine learning algorithm came to a conclusion that SPRP1 can indeed solve hair loss problem. SPRP1 upregulation seems to interfere with WNT signalling.
Thank you!
https://omegatherapeutics.com/our-portfolio/#pipeline
Yoda/Sonic.
Long term propecia user, 18 yrs and rogaine now for about 6. First things first they freaking Work!! Key to success is to get on treatments as soon as you start losing hair. Nw1.5 to nw 2.5. This is where you will get results. If you hop on at nw 3.5 or higher it will take a great responder to gain massive regrowth. It exists but very rare. Neither of the drugs are meant to cure baldness. They can halt it for several years or slow it down drastically. For me it slowed it down drastically for the first 12 years then it kind of lost its effects so I doubled my fin dose and added compound minox which slowed down the balding. When I first started propecia my hair shedding at 20 yrs old stopped in 3 weeks. It worked. Got some minor regrowth in my slightly diffused scalp and it thickened it up to where it wasnt noticable. I was a nw 1 but diffusing quickly. Propecia stopped my loss and thickened my hair all around. I didnt use rogaine till 12 years later. My point being HOP ON TREATMENTS EARLY!!! If you wait then nothing will work as well and you will blame propecia or rogaine not working. These are MAINTENANCE drugs and if lucky you get regrowth. Now for sides, they exist. I got some erectile issues my first year. Those went away after a year and have no issues since. Most of it could have been mental but I’m pretty sure it was propecia causing the side effects. I didnt want to be bald at 21 yrs old at my prime so I kept with the drug. Propecia is also a bph drug that has been out since early 90s with a good safety profile. Drugs affect everyone differently. So it’s not wise to say propecia will make you sick and will mess you up while for others the drug works and no sides. All medications have sides for some and none for others. My advice to newbies….hop on propecia first at first signs of thinning. Speak to your doctor and not someone from the internet…see how propecia goes for a year or so. If you are a low norwood like 1 to 2 dont even bother with rogaine until you see that propecia isn’t maintaining. If it maintains then stay just on propecia for as long as it works. If you see rapid thinning or something then add rogaine. Best to use one treatment propecia first since it hits the root of mpb. Add rogaine later. If nw3 or 4 then hop on both. Also use nizoral 2% and a good hair vitamin. Exercise regularly and drink lots of water and dont smoke.
Thsts my advise. Hope it helps
Darn it Mjones…there you go interjecting logic into irrational arguments! Thank you for the thoughtful post, I agree.
Thanks Mjones for sharing your experience with Finasteride. It seems even you unfortunately had sexual side effects like many others on Finasteride, and whilst it worked for you, it doesn’t mean it would work for everyone, which is what I said. Just like how I said not everyone would get side effects, but many do.
People can try Finasteride and if they get sides they can stop, but many people even after stopping still continue to have permanent sides which is one of the more more common issues becoming more evident and is a reason many chose to steer clear of it. For that reason I personally don’t advise people to try something that has the potential to have irreversible side effects, not just sexually but mental side effects are really real to according to studies
This guy is unreal! Stop with the fear mongering already Sonic. We get it, fin didn’t work for you and you had sides. You found some studies (peer reviewed?) that reinforce your negative opinion of the drug. The way you present your case is that no one should take fin because of your experience and you advise people what to do rather than consulting a medical professional. You picked what you wanted out of Mjones post to further make your case.
Admin, seriously with HLT down it will bring the loons over to your site and infect it with BS. Hopefully you come up with a new article soon so there’s a shiny new object to distract.
No Yoda, you picked out from what I said to further your narrative. I clearly said “not everyone will get sides, but many do”. If you think that’s wrong then there’s something wrong with you.
Furthermore, nothing I said in my response to Mjones was false. Imagine me talking about the potential side effects is being called “Fear Mongering”, LOL. Those are real possibilities. Don’t like it? Too bad, that’s the potential side effects of Finasteride unfortunately.
Not warning people is actually a disservice. Furthermore, even Mjones mentioned he had sexual side effects and you still expect people not to talk of the potential side effects because it makes YOU uncomfortable? LOL. Sounds very narcissistic of you, Yoda.
If you want to be disrespectful, I’ll have you know I’ve been on this website for over 5 years. I tried to be respectful but you’re clearly as ignorant as they come. You’re only happy as long as no one talks about the ugly truth about Finasteride. Well I’m not here to make you happy. I’m here to help people and sugar coating the dangers isn’t helping anyone. You on the other hand need another article to “distract” people away from this topic. You’re also the same one who turned down my multiple attempts to show you privately the plethora of studies and now you make false claims about the type and quality of the studies without even seeing it. LOL, typical boomer. And unfortunately whether you like it or not, more and more studies and reviews from verified sources and medical professionals will continue to come out confessing the potential dangers of Finasteride.
As I said, a guy named “Sonic” has been on HLT for years spreading this same sort of “information”. I was a lurker on that site, never posted due to the number of very angry people that do, Admin can attest to that. Unfortunately (or maybe fortunately) that outlet is gone, maybe for good and folks like Sonic need to keep letting off steam. I never attacked you personally, only your posts. You feel the need to attack me as a person…or some persona known as Yoda. Forget what I said about wanting you to be happy, for some that state doesn’t exist. Yoda will go in peace now, hopefully that cesspool known as HLT get’s back up and you can take your views elsewhere sir!
And as I repeatedly mentioned, my username on other forums isn’t Sonic. It’s only Sonic here. Infact the username was taken already on that forum. BTW, there’s many highly intelligent people on HLT, many of whom are more knowledgeable and have are actual professionals in medical fields and science. It’s one of the biggest hairloss forums for a reason so trying to call an entire forum a “cesspool” is prejudice.
Just like there are people in this web site of people who aren’t knowledgeable in the field of hairloss, it’s not wise to call the entire website a Cesspool. Yoda has shown me his username is just that, a username and definitely not that he is as wise as the real Yoda. And btw you said “with HLT down it would bring the loons over to your site” which was meant to be an insult. So I returned the favor.
By the way, the Hairlosstalk forum is still up and running perfectly well.
And no, I will not take my viewa elsewhere since you do not own this website and the same could be said about you regarding your views.
I will however stop this topic here if that was your last message and you do truly go in peace.
https://link.springer.com/protocol/10.1007/978-1-0716-
Yawn, it’s a beautiful day here in San Diego. Hope everyone is enjoyning thier summer. 😉
Sonic sides are real but please dont fear monger the young kids that join this site into scarying them from taking an Fda approved drug that has the best chance of stopping or slowing down hair loss. Nothing else will work as well until a new drug comes out which can be years. I’m sorry to hear you got sides and that propecia didn’t work for you. I said in my post this drug works best at early signs of hair loss not when you are a nw4 or higher. If you started in that territory then I agree it wont do much for you in terms of regrowth but it might have slowed things down for you….did you see signs of reduce shedding? Did you take brand name propecia? The generics vary in formulation and may not work for some while brand name might work better for others. I did get sides but they went away. Propecia also cured my crazy acne too:) My dht levels as a teen and early 20s were through the roof…acne cleared, hair loss stabilized and my crazy high sex drive went down to normal. My erectile issue went away and I am glad i stayed on propecia. I didnt join forums back in 2002 and glad I didnt because i would of freaked out listening to posters like you…..I listened to my doctors and got my blood work and my dht was low level range around 19 where its supposed to be when on propecia. Sides went away and I kept my hair for all this time. Now if propecia doesn’t work in stopping, slowing and or regrowth then yes drop the drug. Just dont go out scarying new guys on here and they delay taking propecia at nw1 to nw2 then when finally take it at nw3 to nw4 it will be too late and will need fue, derma stamp and some random black market drugs to get growth. Plus all those studies online could all be bs or they could be real. I dont trust the internet. I talk to my doctor and pharmacist who prescribe this drug for over 20 years. I hope you find something that will keep your hair man…I really do because this mpb sucks and having to take meds sucks but I’d rather deal with slight sided than deal with nw7 land and being miserable my whole life or my younger years of life…….also erectile dysfunction isnt just caused my propecia lol….many of these younger guys are addicted to porn and rub 5 out a day lol….that is a big issue with younger guys now and causes erectile issues…bottom line all drugs have sides. All of them!
Mjones, this word of “Fear Mongering” is Actually only used mainly online. Imagine a doctor telling you the potential side effects of a treatment and you tell him, don’t speak you’re “Fear Mongering” LMAO. Coz that is exactly what you are doing. It is Actually by law in many countries that doctors tell you the potential side effects of the treatments or surgery, this term “Fear Mongering” used to tell people online who talk about the potential sides is the most ludicrous degen thing I hear on the internet, definitely not done by Medical Professionals.
BTW, I used original Propecia not generic. I also used Propecia at the first sign of hairloss when I was Norwood 1.5 and it did not reduce any shedding, Infact it caused far more shedding consistently over the 2 years that I used it with barely any stopping. It made my hair far more thinner and made my hairline receed and my scalp show in a diffused thinning pattern which could be seen in sunlight and under lighting.
I kept going onto hairloss forums and hearing people say, “don’t worry about the shedding it just means it’s working” or “don’t worry about the sides, it’s all in your head or they will go away once you stop Propecia”.
All of that was BS. Because online, at the time, you used to get far more people refusing to believe/telling people there’s any sides or that Finasteride could actually make your hairloss worse. It was like a cult by the pro-Finasteride people.
I went from a NW 1.5 to a NW 3 with Finasteride after 2 years. I decided to stop eventually and not listen to all of the BS people were telling me because I knew for a fact that I had gotten sides after Finasteride. Fortunately I had medical testing done before and after so it wasn’t none of the BS the people online had been telling me and others like Propaganda. Finasteride did have a lot of side effects on me.
Furthermore, after stopping Finasteride for 6 months my hair started to get thicker and I went back to a NW2 or NW2. 5 after about a year after stopping Finasteride. My hair felt and looked so much better and thicker after stopping Finasteride.That’s when I knew Finasteride actually made my hairloss worse when I was on it, especially since after stopping Finasteride, once my hair recovered a bit, I pretty much maintained a NW2/NW2. 5 for 6 years now.
So all of the nonsense about “Your hairloss will get worse if you don’t get on Finasteride at the first sign of hairloss” was clearly BS.
So there’s no more excuses pro-Finasteride users can tell me.
BTW, I had mental and sexual side effects that lasted me many years after stopping Finasteride. It was only a few months ago (6 years after stopping Propecia that the mental side effects went away) and most of the sexual side effects of Propecia haven’t gone away. So that “Sexual sides will go away” was obviously another lie.
It was after that point that I went onto major hairloss forums and did some research on reviews from people who had similar results and to my surprise, there were a LOT of them.
I already had seen several studies confirming my suspicions about the side effects of Propecia but it was only once I joined a few Hairloss forums and spoke to some really intelligent people did I manage to acquire far more evidence from verified sources, medical professionals and proper studies about the dangers of Finasteride.
I will say, I didn’t see any of these studies before, it was surely well hidden but I was glad I found them.
Over time I gained exponentially more studies and verified sources and medical professionals confirming what I knew.
So yes, as even you said “Sides are very real”.
I’m glad they eventually went away for you, but also have some respect for those who do get sides that don’t get away to share their experiences, especially since there’s a lot more than just a few people speaking out nowadays.
I’m really glad to note the huge increase in people speaking out about thier side effects on Finasteride on the internet as it’s not something many do even though they have sides. Men typically like to suffer in silence and most often don’t like to talk about this kind of stuff as they like to act Macho.
But if I can help others and change the narrative from pro-Finasteride people saying everything bad about Finasteride is false to showing people how the bad things are actually very real and there’s LOADS of information, proper studies, and testimonials even from Verified Medicak Doctors on social media, then I’ve done by part to help humanity.
Once again, I didn’t say everyone who uses Propecia/Finasteride will get side effects, but many will, and often some sides are irreversible, and that’s a fact.
There’s a reason why many of the upcoming treatments in the pipeline mention providing a solution without the side effects of Propecia/Finasteride as a huge selling point.
There you go again Mjones, interjecting logic again! 🙂 I’ve leaned from another poster is that we should take the word of someone on the internet as being equivalent to a doctor. Also is that “mental” side effects must exist.
I’ve been following this thread between Sonic and Yoda and I must say, I’ve always kept quiet about the side effects of Finasteride even though I had experienced them both sexually and mental side effects, but it was too embarrassing as a man to admit it, but Today I will speak out thanks to Sonic being brave enough to share his thoughts.
It’s typical people like Yoda who keep telling people sides aren’t really common or those like Mjones telling people not to “fear monger” which has kept many people quiet, but no more. How can I be a victim of Propecia side effects and be quiet just because some random old man on the internet like Yoda who isn’t very knowledgeable clearly and calls people from HLT “loons” and calls HLT as “Cesspool” when there are loads of people far more educated and intelligent than him there.
FYI Yoda, even the admin of Follicle Thought has an account which he occasionally uses on Hairloss Talk.
You proved your prejudice the moment you tried to insult those from that forum. You showed your true colors and how little you really know about anything.
You also refused to see the studies about how bad Finasteride can be that Sonic offered multiple times to send you privately but then keep talking about taking only the opinions of peoples experiences on the internet as if there’s no other proof besides peoples testimonials? ROTFLMAO.
You’re a typical boomer who can’t grasp new information it seems and you clearly have a fixed mindset that had now become blatantly obvious that you aren’t even willing to listen to. Anyway, I hope Sonic doesn’t waste his time trying to convince a nobody like you who thinks they know it all and acts as if you own this website when you don’t.
Another poster that feels the need to insult people personally, so sad! 🙁 This forum looks like it will take a turn for the worse. To be clear, Yoda only attacks arguments, cites data and compared some recent posts to one’s he has read on the aforementioned dying forum.
It’s funny how you forget that you were the first one to start with the insults, calling people from other hairloss forums “loons” and a “Cesspool”.
You only don’t like it now that people are speaking up to defend themselves. Too bad.
Also, if you only cite data, you would have had an opened mind to viewing other data which was offered multiple times. And to further highlight this, you made a comment about another hairloss forum calling it dying when there is no proof of that, HairlossTalk is still up and running perfectly well, so not sure where you got that “data” from. It’s also one of the biggest hairloss forums on the internet for a reason. Even the admin of Follicle Thought has an account.
Stop your prejudice and have more of an open mind and you won’t find yourself in such situations. There’s loads of studies around that point out how bad Finasteride is. Ignorance may be bliss to you but it costs people a lot who end up with sides.
When is bayer likely to be done with phase 2.have they even started it?
I never directly called anyone a loon however Pegasus is another HLT poster that has gravitated to this site to express his anger, I mean views. How do the ladies like that son? Take that frown and turn it upside down. 🙂 Admin goes on that site typically only to defend accusations made against him/this site by shall I say the loons.
When I go to that site what I see is copied below, maybe it’s me. In any event my OPINION is that it’s been going downhill for the past few years. I mainly look at it out of habit or like a car wreck on the freeway, there very little information of any value.
Yoda you didn’t direct it at anyone, you directed it at everyone from HLT which is even worse, you said “with HLT down it would bring the loons over to your site”.
That’s prejudice.
Also, I didn’t gravitate to this site simply due to anger, I use a large amount of websites to get information, one of them is this one that I occasionally only browse and don’t usually comment. It just so happened that I saw this comment of yours which was really not wise.
Also, I have a wife, so yeah she loves it, no frowns, another wrong assumption you made.
Furthermore, I know very well about WordPress, it’s actually really easy and I can create a web page in around 5 minutes using WordPress. So there you go again, making another assumption about people based on no knowledge.
The “error” must have been really short lived on HLT because I’ve been frequently on the website with no issues.
Thanks for pointing out that it is only your “OPINION” about HLT and not a fact that it has gone downhill when it is as active as ever. As long as you follow the right threads, it is really good and a lot can be learned with a lot of really intelligent and educated individuals.
I asked a question, happy for you that you were able to find a woman that loves you for who you are. Do these intelligent and educated individuals post their degrees on-line? Even if they don’t have degrees they could be intelligent or well read but not educated. Maybe you consider people that validate your own point of view to be intelligent and educated individuals.
Some individuals you can become friends with via DM, and learn their real names, then it’s a simple search on LinkedIn to see that they really do have expertise in the field or are intelligent individuals based on what qualifications they have under their belt and work experience. Of course that is not the only measure but I was answering your questions.
You can also tell a lot about a person by the posts they make in terms of their understanding of topics and it’s intricacies, especially when they are knowledgeable on many different systems, and processes in the body and pharmaceuticals. Also, smart people have open minds and don’t pretend to know everything, and welcome new views and learning opportunities, something you weren’t able to do and you had a completely closed off mindset.
If everyone pretended they knew everything they’d never learn more than the little they know.
Once again, you made another assumption that was incorrect saying I assume people to be intelligent simply because they agree with what I say and that is completely false. In the paragraph above I mentioned how I am able to determine an intelligent individual, and btw it has nothing to do with qualifications as being well read and open minded is also a key component of being smart.
So it’s best you just stop talking because you keep making yourself worse and worse with all these false accusations. Son.
Of course people can be intelligent without any degrees, however a sure sign that someone isn’t smart is when they pretend to know everything, don’t have an open mind to listen to other veiws and learning opportunities and make a lot of false accusations, which is what you were doing.
And of course they don’t display their qualifications on the forums, but it can be seen that someone knows a lot about Hairloss when they know the technical details, the little intracicies, how the body and systems work, people who have cross functional knowledge as well about different fields. Understanding of molecular biology, biochemistry and molecular biophysics, etc
Also, with forums you can get to know people and make friends via DM, once you learn their real names you can check their LinkedIn profiles, etc.
And no, I don’t assume people to be intelligent just because they agree with me. I explained in the paragraphs above how I can determine if someone is intelligent.
So once again, you’ve made yet another false accusation. It’s best you just stop talking about all this Yoda, you are making yourself look more and more worse.
Bayer/Hope has not started the phase 2.
It’s crazy how people continue to take a drug even after noticing side effects. Like wtf?
Exactly. It’s mainly because they are fed Propaganda by people online trying to convince them into thinking the sides are all in their head and it’s just a coincidence that has nothing to do with Finasteride/Propecia. It’s obviously a really weak excuse.
People who were perfectly healthy mentally and sexually, and only after using Propecia they get mental/sexual issues and they expect people to believe it’s not due to the only change they made (taking Propecia/Finasteride) is the most ludicrous thing on the internet.
@sonic , nobody is telling fin is the equivalent to an Elixir, it does have negative side effects ( for some , FDA says for 98% its safe, and since you don’t trust the FDA(LoL most new treatment which you are waiting for is gonna pass through a FDA trial) am taking the stats to be closer to side effects free for 80% , so let’s not deter those who can save their hair by taking fin without sides. Everyone should take professional help and decide on their own. Young people will get a nocebo effect before even taking fin, when they read your comments. And Let’s keep the fin debate to” Tressless ” and focus on something which more revolutionary , which we all can take and have a full head of hair without any worries. Peace!
I would say even 80% is still far too less compared to the the much higher amount of people who reported getting side effects from a plethora of relatively new proper studies. It was actually the opposite way around with some studies showing around 40 to 60% getting sides on Finasteride.
And Yes I know Finasteride isn’t an Elixir, but it’s also nowhere near as good as the some of the studies done on it claim. That’s clear to see by just how many people still using Finasteride have hairloss/worsening and a lot of bald people around. If Finasteride had such a high efficacy rate, majority if the population would have good heads of hair, which isn’t the case obviously.
People have a better chance stopping hairloss/getting regrowth and thickening by using Micro-needling + Minoxidil with less side effects.
If even say using Oral Minoxidil might yield better results than Finasteride with less side effects
And Yes of course I don’t believe the FDA. The pharmaceutical industry in general is probably one of the most corrupt industries in the world. They would rather have a treatment than a cure as it benefits them more. Every industry in the world has corruption, and expecting the FDA not to have any in naive. We’ve seen even Presidents of America get away with corruption and wrong doing.
For that reason, even though I’m not Chinese, I have a lot of respect for them, in that they don’t allow international companies to influence them. Just look at their medical system whereby they fast track valid treatments to market in record time. They cut out all the BS and delays. If something works, they release it to the people, they don’t wait 7 to 15 years like the FDA can.
Take a look at Kintors Pyrilutamide, it’s flying through trials in unprecedented time in China.
And no, fortunately some of the treatments I hope to see in the pipeline are being trialed in China/Japan too. So it makes it more difficult for the FDA to slow down when it’s making waves in China/Japan.
I’m pretty sure we’ll see the first new hairloss treatment that underwent full clinical trials be released in China 🙂
Thanks Shayak, but why post statistics from the FDA when we can read what another poster thinks are the real numbers? 😉
@Alwayspain nobody takes a drug if he/she experience side effects, some side effects of fin does goes away once your body get adjusted to it. Some people do get side effects continuosly and for them fin is not good.
“Nobody is a strong word” Shayak. Many people continue hairloss treatments especially fib despite getting side effects because they’ve been told side effects will go away, which is often not true. I am proof of one of those people who continued using Finasteride for a full 2 years before deciding to stop
Sorry to hear that, if you experience side effect from the beginning and the side effects does not subside, then a person should either lower their doses or think about taking it. A good doctor will always tell you to asses for two months and see the reaction, two years is too long , that’s why taking help of a learned professional should be of the highest priority. Anyways let’s look forward to more advanced and better treatments. Cheers!
Thank you Shayak. I actually did reduce the dosage and used it only 3 times a week after te 1st year because I read that it would still be sufficient to block DHT. But then as we are learning with new technologies and studies blocing DHT in any way or among is Actually bad, hence we are now seeing different approaches to DHT like those from Kintors Pyrilutamide, GT20029 and Breezula
And Yes, let’s change the topic back to better future treatments in the pipeline 🙂
Cheers!
Thank you Shayak. I actually did reduce the dosage and used it only 3 times a week after the 1st year because I read that it would still be sufficient to block DHT. However, it did not stop the side effects unfortunately.
But then as we are learning with new technologies and studies, blocking DHT in any way or amount is Actually really bad, hence we are now seeing different approaches to dealing with DHT like those from Kintors Pyrilutamide, GT20029 and Breezula
And Yes, let’s change the topic back to better future treatments in the pipeline ?
Cheers!
My goodness! Hahaha talk about stubbornness on this site. Sonic, Pegasus. I never said that propecia wont give you sides or that I didn’t believe propecia made your hair loss worse. I do believe you. Drugs can have bad effects , reverse reactions etc. If you saw propecia making your hair worse then yes propecia didnt work for or the drug itself accelerated your hair loss. I totally agree that happened to you. I’m glad your hair thickened up after you stopped. I immediately saw a reduction in shedding and halting of my hair loss within a month of using propecia. So obviously it worked for me. Fear mongering may be a bad way of saying so I’ll just say you are scarying new kids on taking something that very well will work for them. We are both right in our arguments and you cant say I am wrong just like how I cant say you are wrong. We are both offering help but on different sides of the spectrum. My doctor did tell me the sides and I went to several doctors. I even went to the university of PA where there dermatology dept is headed by cotsarelis. They told me the same thing. Sides are for 2% of the population. I will just say to all new people, try propecia because if you dont you will go bald. Rogaine and needling wont be good enough alone. All new drugs in the pipeline will have sides. Dont be fooled. Msybe worse sides. Nobody knows the future. One thing is if you see your hair getting worse while taking propecia, watch it closely…if it gets worse past 3 to 5 months then drop it. Probably not working. If you get sides that are bad and they last longer than a year then drop propecia if you cant deal with the sides. Nobody is forcing you on these forums. Your body your choice. I am just expressing my success and I am sure millions of others on the drug that kept their hair over 10+ years.
Well said Mjones, can’t say I agree with everything you wrote but close enough. Unlike some other posters you didn’t present your opinions as facts, with numbers pulled out of thin air. Sure, I know there are studies out there that may backup some of these negative statements. What is the quality of these studies? I think it’s time to move on from the stubbornness, name calling and negativity. Yoda will accept some responsibility for the “tone” however this has become a fruitless endeavor. As the kids say haters gonna hate.
You’re a moron Yoda. Why even bother?
Another brilliant post directly calling me names. Apparently this is what self-confident, successful, intelligent people do. 😉
look at the way you initially replied to the other recipients. Don’t get upset just because I’m giving you the same treatment
Gotta completely agree with Alex on that. Yoda was the one to start the name calling then play victim. Come to think of it, I do recall him mention in a comment section in one of the old threads about him mentioning he had suffered from Brain Fog after taking Finasteride for so long. Makes sense why he keeps forgetting details and Sonic, you and myself have repeatedly reminded him of it.
But he wanted to make it seem as if side effects on Finasteride always go away 😉
Good memory Pegasus, because even I recall Yoda mentioned he had some sides from long term usage of Finasteride in an older thread on this website.
I literally had to remind him several times I he was the first one to start insulting people from HLT and then again I had to remind him about the dozens of studies I had willing to share but he kept refusing and forgot I had more evidence than just testimonials of people on hair loss forums.
You three should get a room already. 🙂 You guys seem obsessed with HLT, just spread your love over there. Hugs and Kisses….yours truly, Yoda!
Welp, I was not checking the comments closely this weekend and came back to the melee. Case is closed now guys in this thread and semi-closed permanently, simply because there’s not much to be gained from discussing finasteride with anonymous people on the internet. If you want to share your own experiences that’s fine, please refrain from trying to advise others on the subject one way or the other.
Finasteride is an FDA approved medication for the treatment of hair loss, it’s prescribed quite commonly and it does come with a warning label for potential side effects. Further discussion on it should be done between you and a medical doctor. That’s it, end of the story.
Segwaying, I think people have noticed there is a new company making rounds. There’s not much info available but I will have a new article coming this week, it may or may not include them. Industry continues to grow.
Thank you Joseph and my apologies for engaging. What you wrote is the opinion that I’ve always attempted to present. I really hope that this forum doesn’t devolve into HLT, imagine that’s your desire as well.
Hi admin, what happened to William Lowry from UCLA with their treatment for MPB. It looked interesting and even Allegan wanted to buy the entire company William Lowry founded.
Here’s the article you posted about it in 2019 but no update since:
https://folliclethought.com/ucla-licenses-lactate-hair-growth-drugs/
I think it’s quite strange how a company with that much of attention from Big Pharma went so quiet.
Sonic, there an update posted 1/20/21 on the Updates page. They are testing analog molecules in preclinical studies I believe.
Glad to hear it! Thank you Admin 🙂
Just curious, do any of you three Amigos (if there are truly three and not one) donate to Follicle Thought through Patreon? Just curious, you seem to have a lot to say on this site so you should. Yoda steps up and does. I couldn’t write that if it wasn’t true, Admin would call me out.
Will certainly take the moment to thank all patrons of the site and lighten the mood! lol If any lurkers are interested in supporting please visit https://www.patreon.com/FollicleThought
No I haven’t donated Yoda, as it’s not for any bad reason. I am grateful for all the admin does and I’m sure the admin knows that just because someone hasn’t donated it doesn’t mean the love or respect isn’t there. Donations/money is not a measure of anything and doesn’t make your comments and more valid than anyone else’s. It’s commendable if you do, but like I said, it should not be something you brag about otherwise you defeat the purpose of a donation. I will also be donating as soon as we get a treatment that actually truly works from the pipeline, not to worry 😉
Hopefully you’ll leave this up Admin, I’d like to clear up some misrepresentations (and unpleasant comments) that have been made about Yoda’s brain fog (just a bit fuzzy, no loss of memory) to clear the air (pun intended). In a nutshell I’ve been transitioning off oral dut to topical, currently oral 1x per week and topical everyday. I had some brain fog develop over the past few years, which is common for older people. I’ve read that some people report this when of anti-androgens and ASKED MY DOCTOR. He indicated that getting off any oral med is preferred, even though he was suspect that there is a link. Therefore I decided to try the topical route. My brain fog has improved a bit, can’t say it’s 100% related or not. Hair has lost a little ground, if I loose more ground I’d go back to oral days as much as needed, even everyday. As I’d related before, I’d been on oral anti-androgens fin/dut since the mid 90’s with no appreciable side effects (some watery seamen at 1st on fin that went away). It saved my hair, I’d have been horse shoe bald many years ago if it wasn’t for fin, then dut. Each individual’s experience can vary, I looked at the data, relied on credible doctors and made the best decision for me. This is a choice that is up to the individual along with consult with a medical professional, not listening to random internet bros (including Yoda).
Ok so here’s the deal. I’m not going to keep checking the comment every 10 minutes and you guys seem to have things you want to say. I’ve restored one comment that was deleted to make it fair. If there’s something you want to “clear up” or explain further, do so until 10pm ET tonight. After that, at the very least comments will be removed with no further explanations given. The issue is not so much in the comments themselves it’s that they will trigger never-ending volleys from the other person.
I have nothing bad to say to Yoda, the only mention of the Brain Fog was of genuine concern because it is a side effect that is very real and he has mentioned if himself before, and we have seen repeated instances of him continously mentioning things that were already addressed or that he had forgotten about.
I believe Yoda and I can peacefully co-exist on this website provided he doesn’t try to make it seem as if the studies/negative sides are not real and I will in turn not comment on his opinions on Finasteride. It’s simple. He can have his opinions on Finasteride but don’t disregard others experiences and proof of studies on the possible dangers of Finasteride which are real.
As I mentioned earlier, I’ve been waiting for this back and forth to stop. Let’s proceed on a more peaceful note.
Sonics greatest hits reflecting his concern.
” you’re clearly as ignorant as they come.
You’re only happy as long as no one talks about the ugly truth about Finasteride.” “LOL, typical boomer.”
“Yoda has shown me his username is just that, a username and definitely not that he is as wise as the real Yoda”.
And lastly “Sounds very narcissistic of you, Yoda.” Lets get one thing straight , Yoda is a pompous A-hole but narcissistic he is not.
I appreciate your heartfelt concern Sonic, sure Alex and Pegasus feel the same. You’ve given me a lot to think about as to where this forum is and if Yoda should play a part, maybe this boomer is just too old and senile. I’ll continue support Admin in his endeavor to bring the news. You should consider donating, so should Alex and Pegasus. We take up a lot of real estate with our comments, it’s the least we can do. Guess you can continue to make it conditional on a treatment that meets your criteria coming up.
Sorry Sonic, forgot to mention what prompted my last response. I saw the comment you made about my brain fog before admin deleted it. This didn’t show concern to say the least. I hope Admin puts it back up for context.
Alright, 10 pm and it’s done.
when ? are ? we ? getting ? an update ? from Hopemed and Bayer ?
I think, when an update becomes available. ?
@FollicleThought you need to put them on your ultimate guide
? when they reach trials
They are starting phase 2 soon https://www.prnewswire.com/news-releases/hope-medicine-announced-global-license-agreement-with-bayer-ag-to-advance-the-development-and-commercialization-of-the-monoclonal-antibody-directed-against-prolactin-prl-receptor-300824750.html
Wrong article… https://enmobile.prnasia.com/releases/apac/hope-medicine-completed-us-56-million-in-series-b-financing-strengthening-capabilities-of-global-innovation-317537.shtml
For anyone who has/had lost faith in Clascoterone/Breezula (I admit I had), updates are available from Cassiopea’s Q2 2021 report. I think for many of us non-fin users Breezula and Pyrilutamide are our potential best bet in the near(ish) future.
“During the first half of 2021, activities were focused on the preparations for the US commercial launch of Winlevi® (clascoterone cream 1 %) and advancing the development of clascoterone solution for androgenetic alopecia (AGA).
The Phase II trial investigating clascoterone solution for the treatment of androgenetic alopecia (AGA) in females was completed in the reporting period. Top line results will be available in 3Q 2021.
Progress was made in the development of a new Patient Reported Outcome (PRO) Questionnaire for AGA which has been requested by the FDA to be used in the future Phase III trials of clascoterone solution for AGA in males.”
https://www.cassiopea.com/2021/07/29/cassiopea-announces-results-for-first-half-of-2021/
@FollicleThought how good is your pipeline of news? It feels like 2021 hasnt been a good year of news for us?
D1 I appreciate your enthusiasm for good news, friend. You’ll just have to take the news as it comes and (hopefully) try to appreciate what’s there. 2021 has been a good year of news so far and I’ve shared multiple exclusives (e.g. Sinclair, Koehler, etc) and new companies already. I understand there were a few dropouts, but we can’t control that, always have to move forward if we’re going to stay on the path.
Source for the Stemson cream comment, James?
They had a vimeo posted on video back in march, talking about their pitch deck and product line up. one of the products was a drug. the video was taken down but here’s a snapshot of one of the HairLossTalk replies. Look anybody can think what they want but after histogen, Tsuji and intercytex failed, like im really debating the shave look or a transplant. I cant keep waiting 5 years like this. To all of you who can, god bless you
“I wouldn’t say that, I don’t understand the science at all. To me, it sounds like wealthy people are about to have a quick and permanent solution to hairloss in the next 2-5 years while the plebs have to wait a decade plus.
Based on that pitch deck, product one is going to be what we’ve all been thinking it would be. Autologous means they will be taking your own blood samples/cells and cultivating them to grow you brand new follicles. Fastest path to market because it will be a niche service that is offered at participating clinics similar to PRP/exosomes. Also the most expensive, probably the insane price tags akin to what Tsuji quoted (100-400k) or similar. Seems that with no mention of trials that it may not require clinical trials at all (which would be amazing even if unaffordable) because of how it’s preformed using a patients own blood cultures.
Product two seems like a similar procedure, however, allogeneic means they will not be your own cells. Similar to a blood transfusion or bone marrow transplant, they will be using banked cell cultures from other people to preform the same procedure. Specifically mentions clinical trials because they’ll 100% need to show that the body doesn’t experience an acute immune reaction and reject the new cells lines. COGS is the costs associated with the product, so it would be 5-10x cheaper to preform on the side of the service provider. We’d need more info here because I don’t understand how they would turn banked generic cells into the same hair type as every person getting this. I’m assuming that the allogeneic cell-lines are not the ones that determine the characteristics of the hair, and that part would come from your own contribution to the process.
Product 3 confuses me. Sounds like it will be a hair loss prevention drug that prevents the DP cells from being degraded and thus preventing hairloss. However the next point mentions hair removal, so who knows.”
Ok thanks for sharing. If you could share a link to the snapshot I would appreciate it. I’ve not seen anything about a drug from Stemson mentioned before and it appears that other readers have not seen it either.
@James Tsuji didn’t fail, he’s currently struggling to raise finance. Stemson is one step ahead of him (raised $$) and they’re steadily making progress to trials, though not as quickly as hoped. Stemson could start trials in 2023 and have a market ready product by the late 2020’s. Also, Stemson’s CEO has never mentioned anything about creams. I wouldn’t get too pessimistic as there’s never been a better time in Hair loss research/funding. Here’s some good advice: Make sure to visit a Trichologist/Dermalogist asap to start treating your hair loss, if you haven’t already. You DON’T want to loose ground while waiting for future treatments.
can you please provide a source for the claim that Stemson is developing a cream?
RIZN is now available for sale guys they sent me a 20% coupon too.
Just ordered the “combo” likely will ditch the pills for 2nd order but we’ll see.
Expectations very low let’s see
What’s the coupon code?
it was in a pitch deck video that got taken down on Vimeo. that video was linkedin on HairLossTalk talk. you can see it on various pages. it was on HairLossTalk for 10 pages. they said drug, could be a cream, foam.
I don’t see the screenshot anywhere.
anyone know it or have seen it?
Sorry James, if you have a quote you should be able to produce a link. I asked several times and I want to make sure readers are getting factual information. Stemson is obviously going full bore towards hair cloning, a cream product would be a secondary thought.
[…] Thought has covered Stemson Therapeutics news here, here, and here. While it is exciting to see Stemson move closer to human trials, it will likely be […]